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NCT05642091 Clinical Trial

Role of Ultrasound Elastography in Pleural Effusion

Pleural Effusion Clinical Trial

Official title:
Role of Ultrasound Elastography in Pleural Effusion

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05642091
Other study ID # Ultrasound Elastography
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date December 13, 2022
Est. completion date August 2026

Study information
Verified date December 2022
Source Assiut University
Contact Mai Assem Abd-elkareem, resisdent doctor
Phone +201000970497
Email maiassem620@yahoo.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Diagnostic performance of u.s elastography in pleural effusion

Description:

Pleural fluid is an extremely common problem however the diagnosis of pleural effusion remain challenging due its diverse aetiologies .transthoracic ultrasound is often the initial tool to help diagnosis of pleural effusion. Ultrasound elastography is a novel ultrasound technology that can differentiate malignant disease from benign disease by quantitatively assses tissue stifness by measuring the degree of distortion under application of an external force (shear wave ) However, very limited studies are available evaluating the efficacy of this novel technique in diagnosis of malignant pleural effusion.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 80
Est. completion date August 2026
Est. primary completion date August 13, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: .patients with pleural effusion above18 year Exclusion Criteria: - patients who refuse to undergone further investigations to reach final diagnosis of cause of pleural effusion .patients with intercostal tube inserted in the effusion before enrollment in the study.

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• ultrasound Elastography
application of shear wave force by ultrasound elastography

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

References & Publications (6)

Bibby AC, Dorn P, Psallidas I, Porcel JM, Janssen J, Froudarakis M, Subotic D, Astoul P, Licht P, Schmid R, Scherpereel A, Rahman NM, Cardillo G, Maskell NA. ERS/EACTS statement on the management of malignant pleural effusions. Eur Respir J. 2018 Jul 27;52(1):1800349. doi: 10.1183/13993003.00349-2018. Print 2018 Jul. — View Citation

Davies CW, Gleeson FV, Davies RJ; Pleural Diseases Group, Standards of Care Committee, British Thoracic Society. BTS guidelines for the management of pleural infection. Thorax. 2003 May;58 Suppl 2(Suppl 2):ii18-28. doi: 10.1136/thorax.58.suppl_2.ii18. No abstract available. — View Citation

Havelock T, Teoh R, Laws D, Gleeson F; BTS Pleural Disease Guideline Group. Pleural procedures and thoracic ultrasound: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010 Aug;65 Suppl 2:ii61-76. doi: 10.1136/thx.2010.137026. No abstract available. — View Citation

Hooper C, Lee YC, Maskell N; BTS Pleural Guideline Group. Investigation of a unilateral pleural effusion in adults: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010 Aug;65 Suppl 2:ii4-17. doi: 10.1136/thx.2010.136978. No abstract available. — View Citation

Jiang B, Li XL, Yin Y, Zhang Q, Zang T, Song WS, Wang XM, Kang J, Herth FJF, Hou G. Ultrasound elastography: a novel tool for the differential diagnosis of pleural effusion. Eur Respir J. 2019 Aug 22;54(2):1802018. doi: 10.1183/13993003.02018-2018. Print 2019 Aug. — View Citation

Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr. Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med. 1972 Oct;77(4):507-13. doi: 10.7326/0003-4819-77-4-507. No abstract available. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary detect diagnostic performance of ultrasound elastography in pleural effusion differentiate between elastisty index in benign and malignant pleural effuison that expressed in kpa by measuring it using ultrasound elastography 3 months
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