Efficacy and Safety of Intravenous and Subcutaneous Secukinumab in Moderate to Severe Chronic Plaque-type Psoriasis — STATURE

Plaque-type Psoriasis Clinical Trial

Official title:
A Randomized, Double-blind, Double Dummy, Multicenter Study to Assess the Safety, Tolerability and Long-term Efficacy of Intravenous (10mg/kg) and Subcutaneous (300mg) Secukinumab in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis Who Are Partial Responders to Secukinumab

Status Completed

Clinical Trial Summary

The study will assess the safety and efficacy of intravenous (10mg/kg) and subcutaneous (300mg) secukinumab in moderate to severe chronic plaque-type psoriasis who are partial responders to secukinumab.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01412944
Study type	Interventional
Source	Novartis
Contact
Status	Completed
Phase	Phase 3
Start date	December 2011
Completion date	April 2013

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT01936688` - A Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous MK-3222 in Participants With Moderate-to-Severe Chronic Plaque Psoriasis (MK-3222-012)	Phase 3
Completed	`NCT00763503` - Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of CD 2027 Spray in Adults With Plaque-type Psoriasis	Phase 2
Completed	`NCT00773734` - Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study)	Phase 2
Completed	`NCT01636687` - Judging the Efficacy of Secukinumab in Patients With Psoriasis Using AutoiNjector: a Clinical Trial Evaluating Treatment Results (JUNCTURE)	Phase 3
Completed	`NCT01258088` - Safety Study of Ointment for the Treatment of Plaque-type Psoriasis	Phase 1
Completed	`NCT01132612` - AIN457 Regimen Finding Extension Study in Participants With Moderate to Severe Psoriasis	Phase 2
Completed	`NCT00852761` - A Study to Evaluate the Efficacy and Tolerability of Topical Therapies for the Condition of Plaque-Type Psoriasis	Phase 4
Completed	`NCT00625326` - Study of Dose-Effect of COL-121 Ointment in Patients With Plaque-Type Psoriasis	Phase 2
Completed	`NCT00521339` - Apremilast Safety and PK Study in Recalcitrant Plaque Psoriasis	Phase 2
Completed	`NCT01876875` - n-3 Polysaturated Fatty Acids-rich Diet in Psoriasis	Phase 4