Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery — PosESS  

Pituitary Adenoma Clinical Trial

Official title: Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery (PosESS-Study) - Study Protocol for a Randomized-controlled Single-blinded Superiority Trial

Status Recruiting

Clinical Trial Summary

This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery.

Clinical Trial Description

The endonasal endoscopic approach (EEA) for pituitary surgery is standardly performed with the patient in supine position (SP). The semi-sitting position (SSP) is routinely used for the traditional microscopic transsphenoidal approach and also for posterior fossa surgery. The SSP results in lower intracranial pressure when compared to the supine position due to decreased venous congestion. As a result, intraoperative bleeding may be reduced, potentially leading to decreased surgical morbidity and improved surgical workflow. Studies during endoscopic sinus surgery have shown a significant reduction of blood loss when the patient is placed in a reverse Trendelenburg position with a head elevation of 30°. This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery. ;

Related Conditions & MeSH terms

• Adenoma
• Pituitary Adenoma
• Pituitary Diseases
• Pituitary Neoplasms

• NCT number: NCT04584866
• Study type: Interventional
• Source: University Hospital, Basel, Switzerland
• Contact: Jonathan Rychen, Dr. med.
• Phone: +41 61 328 51 84
• Email: Jonathan.Rychen@usb.ch
• Status: Recruiting
• Phase: N/A
• Start date: January 22, 2021
• Completion date: June 2024