Clinical Trials Logo
  1. Home
  2. Pituitary Adenoma
  3. NCT04074642
  4. Details
NCT04074642 Clinical Trial

OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study.

Pituitary Adenoma Clinical Trial

— FIRST  

Official title:
OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04074642
Other study ID # 19-AOI-06
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date November 14, 2019
Est. completion date February 22, 2023

Study information
Verified date March 2023
Source Centre Hospitalier Universitaire de Nice
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The aim of the study is to assess accurancy of OCT angiography as a pronostic marker for patients undergoing neurosurgery for compressiver macroadenoma as compared with visual acuity, visual field and OCT.

Recruitment information / eligibility
Status Completed
Enrollment 21
Est. completion date February 22, 2023
Est. primary completion date February 22, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - pituitary compressive adenoma (for experimental group) - pituitary non compressive adenoma Exclusion Criteria: - retinian disease - amblyopia - parkinson disease - pregnant woman

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Neurosurgery
adenoma removal

Locations
Country Name City State
France CHU de NICE Nice
France Hôpital Pasteur 2 - Service d'Ophtalmologie Nice

Sponsors (1)
Lead Sponsor Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary change of middle deviation visual field evolution assessed by Middle deviation before surgery (= inclusion), 4 months after surgery and 10 months after surgery
Primary Change of visual function index visual field evolution assessed by visual function index before surgery (= inclusion), 4 months after surgery and 10 months after surgery
See also
  Status Clinical Trial Phase
Recruiting NCT04081701 - 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. Phase 4
Completed NCT01689064 - Comparison of Surgical Approach to Endoscopic Pituitary Adenoma Resection N/A
Recruiting NCT04611685 - Pain Management After Transnasal Transsphenoidal Surgery for Pituitary Adenomas N/A
Completed NCT04212793 - Detection of PitNET Tissue During TSS Using Bevacizumab-800CW Phase 1
Recruiting NCT02709863 - Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function Tests N/A
Completed NCT01465672 - Copeptin as a Diagnostic Marker in the Management of Neurosurgical Patients With Disturbance of Water Homeostasis N/A
Terminated NCT00798057 - Proton Radiation Therapy for Pituitary Adenoma N/A
Completed NCT01504399 - Rhinological Outcomes in Endonasal Pituitary Surgery
Recruiting NCT01556230 - Prospective Study of Clinically Nonfunctioning Pituitary Adenomas
Recruiting NCT04621565 - Hydrocortisone Use During Peri-operation for Pituitary Adenomas N/A
Completed NCT04076046 - Multicentric Prospective Validation of the Zurich Pituitary Score
Not yet recruiting NCT03714763 - Dopamine D2 Receptors(D2R) Imaging in Nonfunctioning Pituitary Adenoma(NFPA) N/A
Recruiting NCT05822817 - Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery Phase 4
Recruiting NCT03164148 - Heart Rate Variability (HRV) in Pituitary Adenoma N/A
Completed NCT04284605 - Effects Exercise Training in Patients With Pituitary Adenoma N/A
Terminated NCT03515603 - Endocrine Outcome of Surgery for Pituitary Adenoma N/A
Not yet recruiting NCT04863456 - Efficiency and Safety of Different Treatment Strategies in Adults With Pituitary Adenomas With Hypothalamic Involvement N/A
Active, not recruiting NCT03465618 - A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors Phase 1
Completed NCT02727686 - Post-Operative Water Load Following Transsphenoidal Pituitary Surgery N/A
Completed NCT02084134 - Peri-Operative Steroid Management in Patients N/A