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Pilonidal Sinus clinical trials

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NCT ID: NCT06206330 Completed - Pilonidal Sinus Clinical Trials

Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus Surgery

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Our study was planned as a prospective controlled randomized study. The study was started after the ethics committee approval received from Dışkapı Yıldırım Beyazıt Training and Research Hospital. (23.08.2021 118/01). Two groups of patients were planned in parallel. In the treatment of pilonidal sinus disease, in patients operated on with the fistulotomy and curettage technique, one group was followed up with classical dressing, while the other group was followed up with PRP (platelet-rich-plasma) and classical dressing. Wound infection, hematoma, length of hospital stay, recurrence, pain in the first postoperative week, and time to complete epithelialization of the wound (in days) were evaluated between the two groups.

NCT ID: NCT05900518 Completed - Clinical trials for Infected Pilonidal Sinus

A Promising Minimally Invasive Surgical Technique for the Treatment of Infected Pilonidal Sinus

LASER SILAT
Start date: June 27, 2018
Phase:
Study type: Observational

Infected pilonidal sinuses are a common pathology, affecting an estimated 0.7% of the population. In France, the most commun technique is extended exeresis with an open wound, followed by directed healing. This technique reduces the risk of recurrence, albeit at the cost of daily nursing care and a long healing period involving prolonged absence from work. Closure or plasty surgical techniques aimed at reducing the duration of nursing care are more restrictive, and seem to have higher recurrence rate. Minimally invasive treatment, such as phenolization and flattening with curettage of the sinus have existed for over 50 years, albeit with disappointing long-term results and morbidity that limits their application. Today, new minimally invasive treatments are being developed, aiming at a less constraining post-operative period. without compromising healing. These include glue, endoscopic treatment (EPSiT : Endoscopic Pilonidal Sinus Treatment or VAASP : Video-Assisted Ablation of Pilonidal Sinus) and laser treatment (SiLaT procedure : Sinus Laser Therapy or PiLaT : Pilonidal disease Laser Treatment). Laser treatment is used since 2014 in the treatment of anal fistulas and more recently in the treatment of infected pilonidal sinus. A laser fiber is introduced, under local or general anaesthesia, into the main cavity and secondary tracts after curettage and opening of the dimples. The energy delivered by the laser is transmitted in the form of heat, in order to seal the cavity during healing of thermal lesions. Initial results report success rates of around 90%, with a healing time of between 1 and 2 months. It also appears to be effective after failure of previous surgery. In cases of incomplete closure or recurrence, a second laser treatment can be performed with high healing rates. The investigators carried out an retrospective study including 29 patients treated with the SILAT technique. The healing rate, defined as the absence of symptoms and recurrence of suppuration, was around 70%. The procedure was painless and no serious complications were observed. The presence of one or more secondary orifices and overweight were associated with a higher risk of failure. In order to confirm these results, to better specify the factors predictive of success, and to evaluate the efficacy of SiLaT in the longer term, the investigators will carry out a single-center study including all adult patients treated with laser between June 2018 and December 2020.

NCT ID: NCT05892198 Completed - Pilonidal Sinus Clinical Trials

A Single Center Experience in the Management of Pilonidal Disease

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

Sacrococcygeal pilonidal disease (PND) is a common entity affecting the skin and subcutaneous tissue of the upper portion of the natal cleft of the buttocks. It is characterized by the presence of sinus tracts with recurrent inflammation and infection. It poses a significant healthcare problem due to its related morbidity, impaired quality of life, and financial costs.

NCT ID: NCT05851690 Completed - Pilonidal Sinus Clinical Trials

Comparison of Two Different Flap Methods in the Treatment of Pilonidal Sinus Disease

Start date: June 16, 2016
Phase: N/A
Study type: Interventional

Sacrococcygeal pilonidal sinus disease (PSD) has been defined as a disease characterized by chronic inflammation and recurrent infections caused by the movement of hair toward the gluteal sulcus. This condition is especially seen in young men and negatively affects the quality of life of patients and prevents them from performing their work and school activities. The treatment options for PSD range from the use of antibiotics alone to reconstructed excision with tissue flaps. Although the optimal surgical treatment option remains controversial, expectations from the ideal surgical treatment include low recurrence and postoperative complication rates, early wound healing, short hospital stay, early return to work, and good cosmetic outcomes. The aim of this study was to compare the efficacy of the different flap techniques in the surgical treatment of PSD and evaluate the long-term outcomes of patients.

NCT ID: NCT05519033 Completed - Clinical trials for Pilonidal Sinus Treatment

Pilonidal Sinus-Turkey

PiSi
Start date: March 1, 2021
Phase:
Study type: Observational

In this research, main purpose is to determine the recurrence prevalence. Destination of the cohort study in which retroprospective data are prospectively reviewed, which aims to identify pilonidal disease subtypes for which various treatment options are indicated, identify various interventions, associate patients with the clinical stage, determine which results are meaningful to patients and which interventions they prefer and provide further research investigation recommendations. . Primary outcome; To determine the postoperative recurrence rates according to the type of surgical intervention. The secondary outcome is; to compare the overall patient satisfaction between different operative techniques and to obtain the ratio of different techniques applied for pilonidal sinus treatment in Turkey.

NCT ID: NCT05404243 Completed - Pilonidal Sinus Clinical Trials

Clinical Trial to Test the Phenolization in Sacrococcygeal Pilonidal Disease

SPQF
Start date: January 1, 2021
Phase: Phase 4
Study type: Interventional

Randomized clinical trial to test the efficacy and safety of phenolization in uncomplicated Sacrococcygeal pilonidal disease

NCT ID: NCT05356208 Completed - Pilonidal Sinus Clinical Trials

Long-term Outcome After Cleft-lift for Pilonidal Sinus Disease

Start date: August 1, 2007
Phase:
Study type: Observational

Single-center cohort study of 10-year risk of treatment failure after cleft-lift under tumescent local analgesia for pilonidal sinus disease

NCT ID: NCT05027607 Completed - Clinical trials for Pilonidal Sinus of Natal Cleft

Long-term Outcome After Pit-pick for Simple Pilonidal Sinus Disease

Start date: August 1, 2007
Phase:
Study type: Observational [Patient Registry]

Single-center cohort study of long-term results after pit-pcik for pilonidal sinus disease.

NCT ID: NCT04856605 Completed - Pilonidal Sinus Clinical Trials

Umblical Pilonidal Sinus Evaluation

Start date: January 1, 2012
Phase:
Study type: Observational [Patient Registry]

Purpose: Pilonidal sinus disease (PSD) is a chronic inflammatory condition of skin due to implanted loose hair. PSD is commonly seen in sacrococcygeal region, but can also be seen in axilla, perineum, suprapubic regions, on hands and umbilicus. The aim of this project was to find factors influencing the development and treatment of umbilical pilonidal sinus. Material and methods: In this cross-sectional prospective study, the investigators evaulated 82 (19 female, 63 male) patients with a history of umbilical pilonidal disease (e.g. predisposing factors, treatment modalities) between 2012 and 2020.

NCT ID: NCT04697082 Completed - Pain Clinical Trials

Application of Platelet-rich Plasma in Pilonidal Sinus Disease

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

Pilonidal sinus disease is a common health-care problem, and surgical excision is the standard treatment modality. Controversy still exists regarding the best surgical technique for treating pilonidal disease in terms of minimizing disease recurrence and patient discomfort. In this study, the investigators compared the impact of autologous platelet-rich plasma (PRP) with that of minimally invasive techniques on pain reduction, return to daily activities, quality of life, and duration of wound healing after open excision and secondary closure.