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Physiological Stress clinical trials

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NCT ID: NCT06084494 Completed - Clinical trials for Physiological Stress

Validation of Heat Stress Limit Values for the Athletic Performance

HSL-AP
Start date: October 21, 2012
Phase: N/A
Study type: Interventional

Three male and three female semi-professional athletes, ranging in age from 22 to 27, participated in a study that was done at Lund University in Sweden to examine their physiological responses. The temperature and relative humidity were adjusted at 40 degrees Celsius for hot, dry conditions and 31 degrees Celsius for hot, wet conditions, respectively. The participants were instructed to engage in physical activity on a treadmill within the chamber for 70 minutes, or until participants were able to continue their exercise without difficulty within the allotted period. Participants were instructed to walk (5 kph) and run (8 kph). Participants pulse rate, breathing rate, oxygen consumption, and subjective reactions were all recorded. On the basis of the Wet Bulb Globe Temperature (WBGT), a heat stress index, the American College of Sports Medicine has made certain suggestions. The technique used to determine the temperature on a Celsius scale took into account the influences of relative humidity, air temperature, wind, and direct sunlight radiation. The American College of Sports Medicine advises delaying athletic competition when the WBGT is above 28 degrees. In the climate control chamber, the trials were carried out in high-risk circumstances (28 degrees Celsius WBGT). According to the study's findings, exercise is influenced by weather, and as air temperature rises, so do the intensity of exertion and thermal feeling.

NCT ID: NCT05832632 Completed - Clinical trials for Psychological Stress

The Effect of Mindfulness on Psychophysiological Stress in a Population With Elevated Stress Symptoms

Start date: November 8, 2021
Phase: N/A
Study type: Interventional

Stress-related disorders have over the last decade increased and contributed to a worldwide disease burden. At the same time there is limited treatment access for mental health disorders, which has left many people without necessary care. However, in recent years there has been a rise in digital mindfulness interventions. Specifically, these interventions have focused on smartphone-based applications as an effective format for mindfulness training programs. Thus, the goal of this randomized controlled trial is to test the effects of three types of mindfulness programs in a population with elevated stress. The three formats of mindfulness interventions are identical in total training duration but varies in content and intervention length. Specifically, the first intervention consists of programmatic mindfulness content that progress over the course of 30 sessions with a duration of 10 min per session. The second intervention consists of single succinct breathing exercises with no programmatic content over the course of 30 sessions with a duration of 10 min per session. The third intervention consists of mindfulness-based content specifically targeted to people with elevated stress that progress over the course of 20 sessions with a duration of 15 min per session. An active control group listening to an audiobook over the course of 30 sessions with a duration of 10 min per session will be employed and a passive control group. The study will evaluate outcomes related to subjective stress, sleep quality, mindfulness and physiological effects of stress using HRV.

NCT ID: NCT05603780 Completed - Sleep Clinical Trials

DEEPTIME: Human Adaptation in Time Underground Isolation

DEEPTIME
Start date: March 11, 2021
Phase: N/A
Study type: Interventional

The objectives of this scientific expedition are: a/ Evaluation of temporal cognitive perception and collective synchronization in a temporally anomalous universe (underground environment), b/ Influence of group living on the endogenous circadian rhythmicity of the central biological clock and peripheral clocks in a "free-running" situation (absence of light/natural darkness), c/Evaluation of cognitive and physiological performance in response to exposure to an extreme environment in a natural underground cavity (cave) without access to a time indicator for 40 days, d/Correlation of cognitive, behavioral, psychological, social, neurophysiological and physiological parameters, e/ Determination of adaptation or maladaptation criteria (biological, genetic, physiological, neurophysiological, psychological and cognitive) in an isolation environment (underground) f/ Study of the evolution of collective organization, decision making and leadership in an extreme isolation and management situation.

NCT ID: NCT05592561 Completed - Clinical trials for Physiological Stress

Impact of Supplements on Stress Markers

Start date: January 25, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine the effects of caffeine, theanine and tyrosine ingestion on markers of stress in healthy college aged individuals that are exposed to a mental stress task. The main questions to answer are: 1. what is the impact of a mental stress task involving a cognitive challenge and virtual reality based active shooter scenario on markers of subjective and biological stress? 2. what is the impact of supplement ingestion (caffeine, theanine, tyrosine, analyzed separately) 40 min prior to exposure to the mental stress task?

NCT ID: NCT05143801 Completed - Hypoxemia Clinical Trials

"Facemask Use During High-intensity Interval Exercise in Temperate and Hot Environments"

Start date: November 25, 2020
Phase: N/A
Study type: Interventional

To investigate surgical mask use and high-intensity interval exercise across different environmental conditions.

NCT ID: NCT04901390 Completed - Clinical trials for Gastrointestinal Dysfunction

Impact of Yogurt on Gastrointestinal Health, Regularity, and Thoughts

IYOGHRT
Start date: September 20, 2021
Phase: N/A
Study type: Interventional

This study aims to test the central hypothesis that adding to the diet daily yogurt provides beneficial effects on digestive health and subjective mood in healthy adults.

NCT ID: NCT04851353 Completed - Pain, Acute Clinical Trials

Multiple Sensory Interventions On Infants' Pain and Physiological Distress During Neonatal Screening Procedures

MSI
Start date: September 26, 2017
Phase: N/A
Study type: Interventional

The study purposes are to compare the effects of different combinations of sensory interventions on newborns' pain responses, physiological distress (heart rate and oxygen saturation), and crying event during heel stick procedures.

NCT ID: NCT04551937 Completed - Cognitive Change Clinical Trials

Effects of Prebiotics on Cognition and Health

EPOCH-2
Start date: February 14, 2018
Phase: N/A
Study type: Interventional

This research intervention aims to examine the effects of prebiotic consumption on changes in behavioral and biological measures of cognition and stress among adults.

NCT ID: NCT04508166 Completed - Clinical trials for Inflammatory Response

Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder

TRAUMA-PRO
Start date: October 1, 2021
Phase: N/A
Study type: Interventional

In this study, we investigate the role that deep sleep plays in the prevention of posttraumatic stress disorder after someone has been exposed to a trauma by boosting deep sleep with two drug conditions compared to placebo condition. Each volunteer in the study goes through all three conditions. The quantity of intrusive memories of the trauma will be compared between the three conditions.

NCT ID: NCT04353076 Completed - Aging Clinical Trials

Physiological Responses in Young and Older Adults During a Prolonged Simulated Heatwave

HW1
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Climate change not only affects the planet's natural resources, but also severely impacts human health. An individual's ability to adequately cope with short- or long-term increases in ambient temperature is critical for maintaining health and wellbeing. Prolonged increases in temperature (heatwaves) pose a serious health risk for older adults, who have a reduced capacity to efficiently regulate body temperature. However, information regarding the impact of age on body temperature regulation during prolonged exposure to extreme heat is lacking, as is research on the effectiveness of interventions aimed at reducing heat strain in such situations. This project will address these important knowledge gaps by exposing healthy young and older adults to a prolonged (9 hour) heat exposure, with conditions representative of heatwaves in temperate continental climates. An additional cohort of older adults will complete the same heatwave simulation but will be briefly (2 hours) exposed to cooler conditions (22-23°C) mid-way through the session (akin to visiting a cooling centre or cooled location). The investigators will evaluate age-related differences in the capacity to dissipate heat via direct air calorimetry (a unique device that permits the precise measurement of the heat dissipated by the human body) and their effect on the regulation of body temperature. The investigators anticipate that older adults will exhibit progressive increases in the heat stored in the body throughout the simulated heatwave, resulting in progressive increases in body core temperature. Further, older adults exposed to brief-mid day cooling will rapidly gain heat upon re-exposure to high ambient temperatures. As a result, by the end of exposure body temperatures will be similar to the group not removed from the heat.