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Phototherapy clinical trials

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NCT ID: NCT06110520 Recruiting - Myopia Clinical Trials

Violet Light for the Suppression of Myopia

Start date: June 7, 2023
Phase: N/A
Study type: Interventional

The study explores the suppression of myopia via violet light.

NCT ID: NCT05949827 Recruiting - Critical Care Clinical Trials

Healing Light Algorithms for Nurses in the ICU

ENGAGE-ICU
Start date: June 1, 2023
Phase:
Study type: Observational

The purpose of this study is to investigate the impact of a newly installed device administering a Light Scheduling Algorithm with high circadian effective irradiances to mechanically ventilated patients on the perceived stress among nursing care specialists. The investigators will further evaluate the impact on commitment to the workplace, meaning of work, and empathy.

NCT ID: NCT05556811 Recruiting - Critical Care Clinical Trials

HEaling LIght Algorithms for the ICU Patient

HELIA-ICU
Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this prospective, randomized controlled trial is to investigate if mechanically ventilated patients who are treated with a Light Scheduling Algorithm with high circadian effective irradiances are better able to preserve and induce physiological melatonin rhythms compared to patients who are treated with an application of lower irradiances. The investigators will further evaluate the impact on delirium prevalence, stress level and general outcome parameters.

NCT ID: NCT04636242 Enrolling by invitation - Shoulder Surgery Clinical Trials

Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis

Start date: August 22, 2019
Phase: Phase 3
Study type: Interventional

This is a prospective, randomized controlled trial to evaluation the ability of 5-aminolevulinic acid HCL topical solution photodynamic therapy to decrease the colonization of Cutibacterium acnes (C. acnes- a bacteria commonly found in the dermis of the skin surrounding the shoulder) in order to decrease postoperative joint infections. -Aminolevulinic acid (ALA) is a naturally occurring metabolite in the synthesis of pathway of cellular heme production. Adding ALA to bacteria encourages porphyrin production which serve as the immediate precursors to heme production. When these porphyrins are illuminated with blue light at an emission peak of 407-420nm, these metabolites become exothermic and cause internal destruction of the bacterial cells. This therapy does not cause any damage to the mammalian cells, which makes PDT safe for human skin treatment.

NCT ID: NCT04407351 Completed - Dementia Clinical Trials

Develop Novel Phototherapy for Health Care of Patients With Sleep Disorder, Mild Cognitive Impairment, or Dementia

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

Investigators aim to collaborate with the division of neurology, ophthalmology and dermatology at the Kaohsiung Medical University, and make a new phototherapy for participants suffering from dementia, sleep disorder, mild cognitive dysfunction by using IoT and data science on big health and environmental data.

NCT ID: NCT04215601 Completed - Phototherapy Clinical Trials

Effect of Phototherapy on Serum Calcium

Start date: February 1, 2020
Phase:
Study type: Observational [Patient Registry]

Through this study our aim was to evaluate whether significant change in serum calcium level occurs in term newborns who are undergoing phototherapy and to find out the association between effect of phototherapy on serum calcium level and birth weight, postnatal age and type of feeding.

NCT ID: NCT03942757 Completed - Preterm Infant Clinical Trials

BiLirubin Decrease Under Phototherapy Exposure in the Preterm Newborn in Incubator

BLUE
Start date: May 2, 2019
Phase:
Study type: Observational [Patient Registry]

Phototherapy is routinely used in neonatal intensive care units for the treatment of jaundice. Guidelines focus mainly on bilirubin serum levels to start the phototherapy. Only few data are available about clinical management of phototherapy devices and subsequently the impact on bilirubin serum decrease. Especially there are no strong recommendations about phototherapy duration, irradiance measurements, incubator temperature and humidity settings. Various factors can influence irradiance and thus the preterm infant bilirubin serum decrease. This study aims at evaluating the impact of an educational program on the use and efficacy of phototherapy in a neonatal intensive care unit.

NCT ID: NCT03752645 Completed - Allergic Rhinitis Clinical Trials

Subjects With Clinical Diagnosis of Allergic Rhinitis Were Randomly Divided Into 2 Groups, With Patients in One Group Given One Treatment Session of Red Light Rhinophototherapy, Followed by Medical Treatment. Those in the Second Group Were Treated With Medical Treatment Only.

Start date: March 2, 2018
Phase: N/A
Study type: Interventional

To investigate the short-term effects of red light rhinophototherapy on nasal patency in patients with a clinical diagnosis of allergic rhinitis using both active anterior rhinomanometry and acoustic rhinometry.

NCT ID: NCT03728439 Completed - Phototherapy Clinical Trials

Effects of Light Emitting Diodes (LED) Therapy in Rugby Athletes

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Therapy with light emitting diodes (LED) is a good resource to accelerate the recovery of the athlete and reduce muscle damage caused by exercise. Objective: To evaluate the effects of LED therapy applied at different times on late muscle pain (DOMS), functional performance, inflammatory and ergogenic response of rugby athletes. Methodology: Randomized crossover clinical trial, composed of three groups that will receive treatment with LED at three different times. Sample made up of rugby athletes of both sexes, aged between 18 and 35 years. On the first day of the study, there will be an anamnesis, where the participants will answer questions about personal data, history of injuries and training time, right after the participants receive weight, height, heart rate and measured blood pressure, in addition to collecting a blood sample. to standardize the individual's baseline values. After the initial assessment, participants will be randomized to not receive the LED (CO) or receive LED therapy at three different times: before (Lpré), in the interval (Lin) and after (Lpós) the performance tests. Then, the modified Star Trek Balance Test (SEBTm), the Single Jump Test (SGHT) and the Triple Jump Test (THT) will be performed. After that, the Bangsbo Sprint (BST) test will be performed, followed by the Yo-Yo level 1 intermittent recovery test (Yo-Yo IR1). At the end of this test, the subjects will remain at rest for 10 minutes and will be subjected to the same tests (BST and Yo-Yo IR1) again. They will be measured at the end of the second battery of tests, heart rate, blood pressure, subjective perception of effort, muscle pain threshold, blood samples collected and repeated functional tests. After 48 hours of the performance tests, the blood sample will be collected again, the functional tests carried out and they answered a Stress Recovery Questionnaire for Athletes (RESTQ-Sport-76). At 7, 14 and 21 days after the initial tests, the same test and evaluation protocol will be performed, but the participants will receive LED therapy before, during or after the performance tests, according to their randomization. LED therapy will be performed on the rectus femoris, vastus lateralis and vastus medialis muscles; bilateral femoral, semitendinosus and gastrocnemius biceps.

NCT ID: NCT03695458 Completed - Phototherapy Clinical Trials

Local and Systemic Effects of Photobiomodulation Therapy on Muscle Performance and Recovery Post-exercise.

Start date: January 14, 2019
Phase: N/A
Study type: Interventional

Recent studies with photobiomodulation therapy have shown positive results in delaying skeletal muscle fatigue and improving performance through levels of biochemical markers and variables related to exercise when this therapy was applied before exercise. Some studies suggest that photobiomodulation therapy has systemic effects, but it is not known whether therapy exerts any systemic effects on human skeletal muscle. With this factor in mind, this research aims to verify the local and systemic effects of phototherapy on muscle performance and recovery after exercise in healthy male participants. This research consists in a randomized, triple-blinded, placebo-controlled trial, with participation of 30 healthy subjects. Will be analyzed parameters related to exercise performance (peak torque in the maximum voluntary contraction test- MVC), delayed onset muscle soreness (DOMS) by visual analogue scale (VAS), and biochemical marker of muscle damage (CK) and blood Lactate (BL). The analysis will be performed before exercise protocol (baseline), after 1 minute of the exercise, and 1, 24, 48 and 72 hours after the end of exercise protocol