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Pharmacological Action clinical trials

View clinical trials related to Pharmacological Action.

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NCT ID: NCT05591105 Completed - Opioid Use Clinical Trials

Morphine Consumption in the Obese Patients

Start date: January 15, 2022
Phase:
Study type: Observational

The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion. The main question it aims to answer are: How lidocaine and ketamine perfusion during recovery period does impact over morphine consumption on the following 48 hours after surgery? All participants will receive total intravenous anesthesia and, at the end of the surgery, they will be divided in two groups, group A: placebo and, group B: with postoperative lidocaine and ketamine perfusion. Our hypothesis is ketamine and lidocaine are a good alternative to decrease the use of morphine in obese patients.

NCT ID: NCT05428683 Completed - Clinical trials for Pharmacological Action

Intravitreal Triamcinolone and Moxifloxacin Injection After Cataract Surgery

Start date: December 3, 2020
Phase: N/A
Study type: Interventional

This study aims to evaluate the short-term effects and safety of prophylactic intra-vitreal injection of triamcinolone-moxifloxacin combination after cataract surgery. 84 patients underwent cataract surgery associated with intra-vitreal injection of triamcinolone-moxifloxacin combination after surgery.

NCT ID: NCT03714360 Completed - Clinical trials for Pharmacological Action

The Effect of Tranexamic Acid. A Randomised Study of Patients Undergoing Elective Lumbar Spine Surgery.

Start date: October 19, 2015
Phase: Phase 4
Study type: Interventional

In this randomized double blind placebo controlled study of tranexamic acid during minor spinal surgery, mean postoperative blood loss in the patients who received TXA was statistically significantly lower compared to placebo.

NCT ID: NCT03522532 Completed - Clinical trials for Pharmacological Action

Dental Restorations Effect on Oxidative Status of the Gingival Crevicular Fluid

Start date: October 2016
Phase: N/A
Study type: Interventional

The goal of the study was to ascertain the influence of dental caries and teeth position as well as the type and amount of the applied dental materials (DMs) on the oxidative stress (OS) status in gingival crevicular fluid (GCF).

NCT ID: NCT03359590 Completed - Clinical trials for Pharmacological Action

Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients

Start date: March 21, 2018
Phase: Phase 2
Study type: Interventional

Sitagliptin, through its effects on sensitizing alpha-cell sensitivity to glucose, can initiate counter-regulatory glucagon responses at higher glycemic thresholds, thus reducing the number of clinically apparent hypoglycemic episodes, and/or ameliorating the severity of hypoglycemic episodes in the case that they should occur. The endpoints have defined such that consequences of this hypothesis can be measured.

NCT ID: NCT03119454 Completed - Clinical trials for Pharmacological Action

"Corticoid-16" in Long Term When Administered Systemically in Patients in Routine Medical Practice

Start date: October 2016
Phase: N/A
Study type: Observational [Patient Registry]

Evaluation of pharmacokinetic parameters of diprospan in long term when administered systemically in patients in routine medical practice. Applied research project. Design: open-comparative prospective cohort study. Two groups of subjects: - patients who are receiving diprospan in standard therapy of their existing disease, or multiple times, but following the introduction of diprospan is planned no earlier than 28 days after the first, - control group of subjects for the study of pharmacokinetic parameters diprospan and its metabolites. Objectives of the study: to evaluate the pharmacokinetic parameters of Diprospan in the long term when administered systemically in patients in routine practice.