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Personality Disorders clinical trials

View clinical trials related to Personality Disorders.

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NCT ID: NCT06433843 Completed - Clinical trials for Posttraumatic Stress Disorder

FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome

Start date: January 2016
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the role FKBP5 DNA methylation levels in patients suffering from complex posttraumatic stress disorder, who participated in a 12-weeks disorder-specific DBT-PTSD inpatient treatment. DNA methylation levels were measured before and after completing DBT-PTSD.

NCT ID: NCT06166693 Completed - Personality Clinical Trials

The Effectiveness of the "MINDLiNG" Digital Mental Health Intervention

Start date: November 23, 2022
Phase: N/A
Study type: Interventional

A study in South Korea assessed the effectiveness of the "MINDLiNG" digital mental healthcare program, targeting maladaptive personality traits, and found significant improvements in reducing stress, perfectionism, loneliness, and anxiety, while increasing self-esteem among participants. The study highlights the potential of digital solutions to address the high demand for mental healthcare services in South Korea.

NCT ID: NCT06076343 Completed - Clinical trials for Borderline Personality Disorder

Integrated Intervention for Borderline Personality Disorder and Caregivers

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

This is a prospective, single-arm, open-label study to assess the impact of a group intervention for patients with borderline personality disorder (BPD) and a psycho-educational intervention for their caregivers. Once participants complete a comprehensive clinical assessment, the study involves the participation of those with a BPD diagnosis in Dialectical Behavior Therapy (DBT) skills training group, integrated with ongoing routine treatments. A battery of questionnaires is administered before and after the DBT skills training to assess emotion dysregulation, BPD symptoms severity and other clinical variables. Simultaneously, caregivers of individuals with BPD take part in the Family Connections (FC) program. This sub-study follows a previous pilot study conducted at the same centre. Family members complete assessment questionnaires at three different time points (i.e., at baseline, at immediately post-intervention and at a 4-month follow-up) in order to evaluate putative positive pre-post changes on burden, grief and other clinical variables. In order to explore biomarkers of BPD and stress-related neurobiological mechanisms, blood samples are collected from the BPD patient group at pre and post intervention. At baseline, a blood sample is also collected to identify stress-related biomarkers among family members.

NCT ID: NCT06074289 Completed - Family Caregivers Clinical Trials

The Impact of a Psycho-educational Program for Family Members of Individuals With Borderline Personality Disorder

Start date: December 16, 2016
Phase: N/A
Study type: Interventional

This is a prospective, single-arm, open-label study to assess the impact of the Family Connections (FC) program on various factors including burden, grief and several clinical variables (i.e., depressive symptoms, family functioning, alexithymia, global psychological distress and anger). It specifically targets caregivers of individuals diagnosed with Borderline Personality Disorder (BPD). The secondary aim of this research is to identify participant profiles that are more likely to experience improvements or deteriorations in their levels of burden and grief. In this study family members are consecutively recruited from four different Italian mental health services and undergo an assessment that includes the gathering of socio-demographic information and completing a comprehensive battery of self-report questionnaires at three specific time points (i.e., at baseline, at immediately post-intervention and at a 4-month follow-up).

NCT ID: NCT06018298 Completed - Mental Disorder Clinical Trials

Evaluation of Excellence in Italy's Residence for Execution of Security Measure

ITAL-EE-REMS
Start date: July 1, 2018
Phase:
Study type: Observational

The model of care for forensic psychiatry in Italy was changed by law (Law 81/2014) so that the six legacy secure forensic hospitals (Judicial Psychiatric Hospitals, OPG) were closed and new secure community residences for the execution of security measures (REMS) were opened in each of the 20 regions of Italy. This transition was in place by 2015. This observational study evaluates the health gains for patients both previously in OPGs and those admitted first to REMS. Health gains assessed include recovery measured by symptoms, function, need for therapeutic security and recovery of legal autonomy.

NCT ID: NCT05831852 Completed - Clinical trials for Borderline Personality Disorder

Screening of the Possible Risk Factors for Borderline Personality Disorders and Validation of Maclean Instrument

Start date: May 1, 2023
Phase:
Study type: Observational

Borderline personality disorder is a mental illness that severely impacts a person's ability to regulate their emotions. This loss of emotional control can increase impulsivity, affect how a person feels about themselves, and negatively impact their relationships with others. In fact, the societal impact of BPDs might be found in emotional suffering, disability and economic burden. In addition in BPD, the suicide rate might be as high as 8-10%. the presence of BPD also interferes with response to treatment of physical and psychiatric comorbidities, such as migraine, HIV, anxiety disorders and substance use disorders. Furthermore, BPD in particular, are associated with high rates of unemployment, absences from work and inefficiency at work, with only 25% of patients suffering from BPD working full time and 40% receiving disability payments. Accordingly, early detection and management would be of great societal and economic impact. Our Study aim is to validate the Arabic version of Maclean Instrument for screening and detection of BPD and and investigate the possible risk factors associated with that disease

NCT ID: NCT05601063 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Ascertaining Diagnosis Classification With Elicited Speech

ACES
Start date: October 1, 2020
Phase:
Study type: Observational

Cross-sectional observational study of the relationship between speech patterns and psychiatric symptoms and disorders.

NCT ID: NCT05516238 Completed - Anxiety Disorders Clinical Trials

Systematic Use of Telepsychiatry for Outpatients

Start date: April 21, 2021
Phase: N/A
Study type: Interventional

Implementation and evaluation of video consultation in psychiatric outpatient treatment. The study will focus on patients' experiences regarding the use of VC. The study will also examine important aspects of the telepsychiatric consultation such as therapeutic alliance, consultation content, psychopathology and satisfaction levels compared to face-to-face consultations.

NCT ID: NCT05484986 Completed - Violence Clinical Trials

Nursing Students' Personality Traits and Competence in Workplace Violence Management

Start date: May 14, 2022
Phase:
Study type: Observational

Aim: The aim of this study was to determine the relationship between nursing students' personality traits and competence in workplace violence management. Background: Violence against nursing students is a growing concern in nursing education, clinical practice, and professional development and needs to be managed. Design: A cross-sectional study. Methods: This study was conducted with 321 nursing students in the summer of 2022.

NCT ID: NCT05453032 Completed - Clinical trials for Borderline Personality Disorder

The Effect of Non Invasive Brain Stimulation on Impulsivity in Borderline Personality Disorder

Start date: May 10, 2021
Phase: N/A
Study type: Interventional

A pilot study to examine the effects of Non-Invasive Brain stimulation on impulsive behaviour in patients diagnosed with Borderline Personality Disorder. patients who received the neurostimulation sessions will be enrolled in short term psychotherapy (3-month)