Kidney Failure Clinical Trial
Official title:
Randomized Trial on Intravenous Antibiotics With Adjunctive Lavage for Severe Peritoneal-dialysis Related Peritonitis
This is a randomized controlled trial to evaluate whether a switch to intravenous antibiotics with adjunctive lavage can improve the outcome of severe peritoneal dialysis related peritonitis.
The standard treatment of peritoneal dialysis (PD) related peritonitis is intraperitoneal
(IP) antibiotics. In severe cases not responding to the IP antibiotics treatment, timely
Tenckhoff catheter removal is needed. There is no known adjunctive measure that can improve
the clinical outcome of the patients suffering from severe PD peritonitis.
Based on the past experience in the investigators' center, switching IP to intravenous route
of antibiotics administration, together with adjunctive lavage was proposed to improve the
clinical outcome of severe PD peritonitis, in particular a possible improved catheter salvage
rate. This method will be evaluated in the present clinical trial.
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