Peripheral Vascular Diseases Clinical Trial
Official title:
Incidence and Progression of Peripheral Venous Disease
Peripheral venous disease occurs when a vein becomes damaged or blocked. It can occur almost anywhere in the body, but is most common in the arms and legs. This study will examine people who participated in a previous venous disease study to evaluate changes in leg veins and venous disease status over a period of 11 years.
Peripheral venous disease is a general term for damage, defects, or blockage that occurs in
the peripheral veins, which carry blood from the hands and feet back to the heart to receive
oxygen. The most common cause of peripheral venous disease is a blood clot that blocks a
vein. Varicose veins, which are swollen blood vessels near the surface of the skin, and
chronic venous insufficiency, a condition in which blood in the leg veins does not drain
properly, are two other common types of peripheral venous disease. From 1996 to 2000, the
San Diego Population Study (SDPS) evaluated a group of individuals to gather information on
the prevalence of venous disease. This current study will re-evaluate the SDPS participants
to document changes that have occurred in their leg veins over the past 11 years, including
any new venous disease and any progression of existing venous disease. Study researchers
will also evaluate how venous disease relates to risk factors, symptoms, and quality of life
issues.
This study will enroll people who participated in the SDPS study. Each participant will
attend one study visit. Study staff will conduct a 1-hour interview with each participant to
collect information on their medical history, disease-related symptoms, risk factors for
venous disease, family health history, health habits, and quality of life. Blood collection
will occur, participant's leg veins will be examined and photographed, and blood flow in the
legs will be measured with an ultrasound.
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Observational Model: Cohort
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