Clinical Trials Logo

Clinical Trial Summary

The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular system, kidney, respiratory system, infection, pain, and other perioperative complications. Based on the database, the investigators intend to explore: - The incidence and risk factors of perioperative morbidity and mortality in elderly patients; - Perioperative risk assessment methods and early warning models for elderly patients; - Practical, safe, and effective risk prevention and control system through subsequent studies.


Clinical Trial Description

As the population aging is speeding up, senile diseases have become a significant and severe public health problem, influencing national health. More than 20 million elderly patients undergo surgery each year in China, accounting for a quarter of the population who undergo surgery. Advanced age and comorbid diseases render the elderly at increased risk of postoperative morbidity and mortality. The incidence of postoperative complications is twice that of non-elderly patients, and mortality rates are five times higher than non-elderly patients. Thus, it is a significant challenge to safely and stably ensure the elderly are in an optimal perioperative period. For the good of optimizing perioperative management, it is urgent to build a large-sample, multi-center database. Based on this database, the investigators can explore new risk assessment methods and establish a perioperative risk prediction model and early warning system suitable for elderly patients. It will help improve this group of patients' short- and long-term outcomes and thus reduce the economic burden of national health and medical resources. In this context, establishing a clinical database including data for all perioperative elderly patients is of high interest. This database will allow the investigators to carry out clinical research on: - Clinical, biological, and genetic factors predictive of perioperative complications and deaths; - Systematic and individualized evaluation tools for elderly patients; - Prognostic factors for improving short- and long-term outcomes. This is particularly significant for rare clinical evidence of perioperative elderly patients for which the current knowledge is scarce. The database will also allow the investigators to develop or participate in multi-center trials, national or international, and facilitate the formation of perioperative data collection standards. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04911530
Study type Observational
Source Chinese PLA General Hospital
Contact Weidong Mi, PhD
Phone 8613381082966
Email wwdd1962@aliyun.com
Status Recruiting
Phase
Start date April 1, 2020
Completion date December 31, 2025

See also
  Status Clinical Trial Phase
Not yet recruiting NCT03994419 - PErioperAtive CHildhood ObesitY
Active, not recruiting NCT01681238 - Goal-directed Therapy in High-risk Surgery N/A
Recruiting NCT05613439 - The Fast-track Centre for Hip and Knee Replacement Database
Recruiting NCT03740438 - Modeling of the Hemoglobin Drop in the Uncomplicated Postoperative Course
Completed NCT03269760 - Multimodal Sleep Pathway for Shoulder Arthroplasty Phase 1
Recruiting NCT05594199 - Feasibility of a Virtual Smoking Cessation Program N/A
Completed NCT00538499 - Fentanyl With or Without Bupivacaine in Reducing Pain in Patients Undergoing Video-Assisted Chest Surgery N/A
Recruiting NCT01690338 - A Study of Residual Curarization Incidence in China Phase 4
Recruiting NCT01110798 - J-Pouch Colorectal Anastomosis or Straight Colorectal Anastomosis in Treating Patients With Rectal Cancer Who Have Undergone Surgery to Remove the Tumor N/A
Completed NCT00859157 - Pain After Tumescent Mastectomy or Standard Mastectomy in Women With Stage I, Stage II, or Stage III Breast Cancer N/A
Withdrawn NCT03531268 - Prospective Study to Evaluate the Clinical Utility of Perioperative Pharmacogenomic Testing N/A
Recruiting NCT04356638 - a Phase III Trial of Safety and Efficacy of Premedication With Dexmedetomidine and Midazolam in Pediatric Patients Phase 3
Completed NCT03579121 - Genomic Opioid Optimization of Dosing and Selections (GOODS) Study N/A
Completed NCT03899441 - Multimedia Aid Gynecologic Counseling and Consent N/A
Recruiting NCT06123039 - Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
Completed NCT01672892 - Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer Phase 3
Completed NCT01510652 - More Options Available With a Quadripolar LV Lead pRovidE In-clinic Solutions to CRT Challenges N/A
Completed NCT01680367 - Wound Dressings For Split-Thickness Skin Graft Donor Sites in Patients Undergoing Surgery N/A
Active, not recruiting NCT00005600 - Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer N/A
Recruiting NCT05743673 - SHAPE Test for Preoperative Risk Stratification