Role of Simvastatin Microsponges in Treatment of Periodontitis

Status Completed

Clinical Trial Summary

the aim of our study is to enhance the dissolution and subsequently the local penetration of the drug through the sulcus in addition to controlling the drug release so that, the drug could be potentially absorbed.

Clinical Trial Description

Patients will be divided randomly into three groups: Group (I);will be treated with subgingival debridement and subgengival injection of chitosan 2% gel containing a microsponges formulated (SV), Group (II); will be treated with subgingival debridement and subgingival injection of chitosan 2% gel containing free (SV) and Group (III); will be treated by subgingival debridement and placebo gel injected subgingivally. Pocket depth and clinical attachment loss bone gain were recorded preoperative and six months postoperative for all groups. ;

Study Design

Related Conditions & MeSH terms

Periodontitis

Clinical Trial Details

NCT number	NCT04836078
Study type	Interventional
Source	Assiut University
Contact
Status	Completed
Phase	Early Phase 1
Start date	February 10, 2020
Completion date	October 10, 2020

View Details

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