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Clinical Trial Summary

A new classification of periodontal diseases was created in 2018. the investigators want to know if this clinical classification is based, or not, on a biological reality. To do this, the investigators will collect data from the clinical examination (clinical assessment and radiological assessment) as well as non-invasive samples of subgingival plaque and crevicular gingival fluid (CGF). The subgingival plaque samples will be analyzed to define the microbiotic profiles of the patients and the CGF determined to define their inflammatory expression profiles. These results will then be linked to the diagnosis of severity of periodontitis.


Clinical Trial Description

In the new classification of periodontal disease, the investigators will seek to know whether there is a specific bacterial signature associated with the severity of damage on the one hand, and the other hand, the investigators will search for cytokinic biomarkers which can be correlated with the severity of the damage.

In this study, the investigators propose to include 25 patients with periodontitis stage I and II versus stage III and IV according to Chicago classification (2018) ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04251650
Study type Observational
Source Nantes University Hospital
Contact Assem SOUEIDAN, Pr
Phone 02.40.41.29.23
Email assem.soueidan@chu-nantes.fr
Status Recruiting
Phase
Start date May 1, 2019
Completion date March 31, 2020

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