Periodontitis Clinical Trial
Official title:
Assessment of Use of Plasma or Serum IgG Test to Screen for Periodontitis
Verified date | August 2012 |
Source | Okayama University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This study was performed to evaluate prospectively the diagnostic utility of a blood IgG antibody titer test against periodontal pathogens.
Status | Completed |
Enrollment | 1387 |
Est. completion date | March 2010 |
Est. primary completion date | November 2009 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years and older |
Eligibility |
Inclusion Criteria: - periodontal patients - adults Exclusion Criteria: - difficulty of communication - received periodontal therapy within 3 months - with other diseases, i.e., hypertension, diabetes (self reported) |
Country | Name | City | State |
---|---|---|---|
Japan | Tokyo Medical and Dental University Graduate School | Bunkyo-ku | Tokyo |
Japan | Nippon Dental University, School of Life Dentistry at Tokyo | Chiyoda-ku | Tokyo |
Japan | Hiroshima University Graduate School of Biomedical Sciences | Hiroshima | |
Japan | Nihon University School of Dentistry at Matsudo | Matsudo | Chiba |
Japan | Nagasaki University Graduate School of Biomedical Sciences | Nagasaki | |
Japan | Aichi Gakuin University, School of Dentistry | Nagoya | Aichi |
Japan | Niigata University Faculty of Dentistry | Niigata | |
Japan | Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences | Okayama | |
Japan | Tohoku University Graduate School of Dentistry | Sendai | Miyagi |
Japan | Osaka University Graduate School of Dentistry | Suita | Osaka |
Japan | The University of Tokushima Graduate School, Institute of Health Biosciences | Tokushima | |
Japan | Toyota Motor Corporation | Toyota | Aichi |
Lead Sponsor | Collaborator |
---|---|
Okayama University |
Japan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Level of IgG antibodies in serum/plasma against periodontal pathogens | Serum/plasma samples will be screened for the presence of IgG antibodies against the below mentioned periodontal pathogens, using the "ELISA" method. Aggregatibacter actinomycetemcomitans, Eikenella corrodens, Prevotella intermedius, Porphyromonas gingivalis |
1 to 3 months after basic periodontal treatment (Scaling and root planing) | |
Secondary | Periodontal pocket depth | Clinical observation on periodontal pocket depth before and after basic periodontal treatment, in order to confirm appropriate effects of the treatment. | 1 to 3 months after basic periodontal treatment | |
Secondary | Bleeding on probing | Judging from bleeding from gingiva after periodontal pocket probing, degree of inflammation will be understood. | 1 to 3 monthsafter basic periodontal treatment | |
Secondary | Tooth mobility | Clinical observation to understand decrease of inflammation | 1 to 3 months after basic periodontal treatment |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04712630 -
Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft
|
N/A | |
Completed |
NCT06127069 -
Treatment of Residual Pockets in Periodontal Patients Using an Oscillating Chitosan Device
|
N/A | |
Completed |
NCT04964167 -
Indocyanine-green Mediated Photosensitizer VS Aloe Vera Gel: Adjunct Therapy to Scaling and Root Planing in Patients With Chronic Periodontitis
|
Phase 4 | |
Completed |
NCT05906797 -
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.
|
N/A | |
Recruiting |
NCT03997552 -
NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration
|
N/A | |
Completed |
NCT05530252 -
Effects of AMP Application After Non-surgical Periodontal Therapy on Treatment of Periodontitis
|
Phase 4 | |
Completed |
NCT04881357 -
Antiplaque/Antigingivitis Effect of Lacer Oros Integral
|
N/A | |
Recruiting |
NCT03790605 -
A Clinical Trial to Study the Effect of a Drug, Curcumin in Patients With Periodontitis
|
Phase 3 | |
Enrolling by invitation |
NCT04971174 -
Outcomes of Periodontal Regenerative Treatment
|
||
Not yet recruiting |
NCT05568290 -
Interleukin-38 Levels in Individuals With Periodontitis
|
||
Completed |
NCT04383561 -
Relationship Between LRG and Periodontal Disease
|
N/A | |
Recruiting |
NCT03997578 -
Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects
|
N/A | |
Completed |
NCT03901066 -
Smoking Dependence and Periodontitis
|
||
Enrolling by invitation |
NCT04956211 -
Periodontal Treatment and Ischemic Stroke
|
N/A | |
Recruiting |
NCT05971706 -
Ozone Application in Periodontal Treatment
|
N/A | |
Recruiting |
NCT06099574 -
A Study on the Oral Health Status of Pregnant Women With Gestational Diabetes and Its Correlation With Oral Flora
|
||
Completed |
NCT04402996 -
Meteorin-like Levels in Individuals With Periodontitis
|
||
Active, not recruiting |
NCT05311657 -
Oral Health and Severe COPD
|
||
Not yet recruiting |
NCT06453278 -
(DDS) in India: a Screening Tool to Identify Prediabetes and Undiagnosed Type 2 Diabetes in Dental Settings
|
||
Not yet recruiting |
NCT05643287 -
The Effect of Time on the Outcome of Periodontal Treatment.
|
N/A |