Periodontitis Clinical Trial
Official title:
Evaluation of Early Wound Healing Following Use of Fibrin Sealant (FS) in Periodontal Surgery. A Controlled Randomized Clinical Trial.
The aim of this randomized controlled clinical trial is to compare wound healing after the
use of fibrin sealant and sutures for gum surgeries. 15 patients requiring gum surgery for
their periodontal (gum)problems are selected and invited. Two regions will be operated in a
selected patient. One region will receive fibrin sealant (test site) and the other region
will get sutures (control site). Wound healing will be assessed by evaluating inflammatory
markers, Interleukin 1beta and interleukin 8, from a non invasively collected gum fluid.
Hypothesis. Fibrin sealant use will result in less inflammation seen through reduced levels
of interleukin (1beta and 8) compared to use of sutures.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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