Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments

Periodontitis, Adult Clinical Trial

— PERIODONTITIS  

Official title:

Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments: Impact of Risk Factors and Treatment Characteristics

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05065034
• Other study ID #: 8333
• Status: Recruiting
• Start date: September 29, 2021
• Est. completion date: June 25, 2023

Study information

• Verified date: September 2021
• Source: University Hospital, Strasbourg, France
• Contact: Jean-Luc DAVIDEAU, MD, PhD
• Phone: 33 3 88 11 69 47
• Email: jean.luc.davideau[@]chru-strasbourg.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Antibiotics are currently used in periodontology to specifically target the most pathogenic bacteria in subgingival biofilms and to improve treatments. The multiplicity of protocols / dosages tested and the variability of the results did not make it possible to reach an international consensus on antibiotic therapy and its cost / benefit ratio, in particular with regard to the significant side effects of taking antibiotics (resistance bacterial). The care environment as well as the clinical, biological and microbiological parameters can strongly influence the results in usual treatment.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: June 25, 2023
• Est. primary completion date: June 25, 2023
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion criteria:

• Patient over 18 years old

• Patient treated for periodontitis between 01/01/2012 and 07/31/2021

• Patient whose medical and periodontal file contains all the elements necessary for data analysis

• Subject not having expressed, after information, his opposition to the reuse of his medical data for the purposes of this research.

Exclusion criteria:

• Patient who expressed his opposition to participating in the study

• Patient without periodontitis

• Patient smoking more than 10 cigarettes / day

• Patient presenting a dilapidated oral state (untreated caries, unrestored teeth), oral infectious foci whose management requires antibiotic treatment during the initial treatment

• Impossibility of giving the subject informed information

• Subject under safeguard of justice

• Subject under guardianship or guardianship

Related Conditions & MeSH terms

• Chronic Periodontitis
• Periodontitis
• Periodontitis, Adult

Locations

Country	Name	City	State
France	Service de Médecine et de Chirurgie Bucco-Dentaires - Hôpitaux Universitaires de Strasbourg	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	A retrospective study of the use of antibiotic therapy on the short and long-term results of periodontitis treatments		Files analysed retrospectively from January 01, 2012 to July 07, 2021 will be examined]