Periodontitis, Adult Clinical Trial
— Paro-Proto 2Official title:
Preliminary Clinical Study of the Presence of Trichomonas Tenax and Entamoeba Gingivalis in Patients With Periodontitis Consulting to CHU of Nancy, in Periodontal Department.
Verified date | November 2017 |
Source | Central Hospital, Nancy, France |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The buccal cavity presents microorganismes whose the number and composition vary with oral
hygiene and medical context (pathologies and associated drug therapies) of the patient. More
than 1200 bacterial species have been identified, and among them, 400 are inhabitants of the
sub-gingival biofilm. Among all these microorganismes, only 20 species participate to the
etiopathogenesis of periodontal diseases.Some are recognised as major periodontopathogens
other play unclear role in this pathology. They belong respectively to the red and orange
complex of Socransky et al. (1998).
Other microorganismes such as virures, yeasts and protozoans could potentially impact the
emergence and development of periodontal diseases. The presence of protozoans in
periodontitis have been investigated in this study.
Status | Completed |
Enrollment | 50 |
Est. completion date | November 11, 2014 |
Est. primary completion date | November 11, 2014 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Adults > 18 years-old - Consulting in periodontal department of CHU, Nancy - Patient with moderate to severe periodontitis - At least 2 periodontal sites with PPD= 4mm and One healthy site - No scaling root planning in the last 6 months - Patients insured under the French social security system Exclusion Criteria: - Pregnant patients - Patients with antibiotic therapy, and/or all medecines which could modify the buccal microbiota in the last 6 months - Tooth with endodontic periapical lesion - Patients having a scaling root planning in the last 6 months - Patient with guardianship |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Central Hospital, Nancy, France |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Presence of protozoans | baseline | ||
Secondary | Periodontal pocket depth (mm) | baseline | ||
Secondary | Clinical attachment loss (mm) | baseline | ||
Secondary | Plaque and gingival index | baseline | ||
Secondary | Mobility of the tooth (Yes/No) | baseline | ||
Secondary | Presence of bleeding on probing (Yes/No) | baseline |
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