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Periimplantitis clinical trials

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NCT ID: NCT03421717 Completed - Clinical trials for Peri-implant Mucositis

The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy

Start date: November 1, 2012
Phase: N/A
Study type: Interventional

Peri-implantitis is defined as inflammation in the mucosa surrounding an oral implant with loss of supporting bone. The goals of peri-implantitis treatment are to resolve inflammation and to arrest the progression of disease. It is important to systematically gather information on the effect of surgical peri-implant treatment and to assess different protocols regarding chair-side maintenance of peri-implant tissue after surgery The aims of this clinical investigation are to evaluate the clinical, microbiological and radiographic outcomes of surgical treatment of peri-implantitis and to evaluate the efficacy of 2 supportive treatment protocols based on the use of titanium cyrettes or by the use of a flexible, biodegradable chitosan brush. Furthermore, to evaluate the impact of this therapy on selected biochemical markers associated with chronic inflammation and bone tissue destruction.

NCT ID: NCT03142828 Completed - Periimplantitis Clinical Trials

Implant Healing Abutment and Chlorhexidine

CHX-HA
Start date: April 15, 2017
Phase: Phase 4
Study type: Interventional

The work hyposesis is based on the application of a chlorhexidine gel against the non-application on the healing abutments in patients who have received a submerged titanium implant to check its effect on healing and prevention of bacterial plaque accumulation during a period of 1 month.

NCT ID: NCT02939222 Withdrawn - Periimplantitis Clinical Trials

Impact of Buccal Bone Thickness on Pathological Peri-implant Bone Loss: A 3-year Prospective Cohort Study

Start date: October 1, 2016
Phase: N/A
Study type: Interventional

Implant placement may trigger bone trauma, which might result in 3-dimensional bone changes. While the process of peri-implant disease is not well understood, implant position within the bony structure might play a role. However, there is no data available on this regard.

NCT ID: NCT02789306 Completed - Periodontal Disease Clinical Trials

Preventive Maintenance Therapy on Peri-implant Diseases

PIMT
Start date: May 2016
Phase: N/A
Study type: Observational

In the field of periodontics, periodontal support therapy has proven to be essential in preventing the incidence or recurrence of periodontal diseases. The protocol is designed according to the risk profile of a patient. For example, in the presence of the history of periodontal therapy, subgingival microbiota containing large numbers of spirochetes and mobile rods can recolonize pockets 4-8 weeks after scaling. Similarly, routine maintenance of dental implants has been recommended to prudently avoid peri-implant inflammation, Indeed, the understanding of the nature of the tissue around the implant and its pattern of disease would be important to consider, even surpassing importance. Recently, a systematic review by our group has identified the importance of maintenance therapy around implants because it can help prevent about 3 times patient-level frequency peri-implantitis. Henceforth, our primary goal was to study the influence in a cross-sectional study of the frequency of peri-implantitis patients according to their post-implant placement and corresponding prosthesis visits supportive peri-implant maintenance. As such, it will be shown: 1. What are the local and systemic factors affecting the appearance of peri-implantitis 2. The ideal frequency of supportive peri-implant maintenance in patients who do not develop peri-implant disease 3. What is the population of patients who come to supportive peri-implant maintenance after placement of dental implants

NCT ID: NCT02375178 Completed - Clinical trials for Periodontal Diseases

Antimicrobial Activity of Two Mouthwashes

Start date: August 2014
Phase: N/A
Study type: Interventional

This is a three arm randomized trial. The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity. A total of 30 healthy volunteers will be enrolled and randomly allocated to control group (CG, n=10), which will be instructed to rinse the mouth with 10ml of a sterile saline solution for one minute, to chlorhexidine group (ClG, n=10), which will be instructed to rinse the mouth with 10ml of an 0.12% chlorhexidine solution, for one minute, or to polyhexamethylene biguanide group (PG, n=10), which will be instructed to rinse the mouth with 10ml of an 0.07% polyhexamethylene biguanide solution, for one minute. Samples of saliva will be collected before the mouth wash and after 30, 60 and 180 minutes. Samples will be plated on manitol agar, mitis salivarius agar, EMB agar and Sabouraud agar. Samples will be processed by a blinded microbiologist.

NCT ID: NCT02185209 Completed - Clinical trials for Periodontal Diseases

Surgical Treatment of Peri-implantitis With and Without Systemically Adjunctive Antibiotics

Start date: March 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate if the use of systemic adjunctive antibiotics in the treatment of periimplantitis is needed.

NCT ID: NCT01954485 Recruiting - Periimplantitis Clinical Trials

Adhesion of Connective Tissue Around Laser-treated Abutments for Dental Implants - Clinical Trial in Humans

Start date: January 2013
Phase: Phase 4
Study type: Interventional

This study aims to demonstrate the histological differences in the connective tissue surrounding laser-treated abutments and untreated abutments in humans. Working hypothesis: There are differences in the adhesion of collagen fibres around implant abutments with laser-produced microgrooves and standard abutments.

NCT ID: NCT00921583 Completed - Dental Implants Clinical Trials

Long-term Examination of Titanium Dental Implants With a TPS Surface: A Prospective 20-year Case Series Study

Start date: June 2009
Phase: N/A
Study type: Observational

Since 1986, newly developed titanium implants with a TPS surface have been utilized for the treatment of partially edentulous patients with implant supported fixed dental prostheses (FTP). In the beginning, these implant types have been sold by Straumann under the brand name "Bonefit implants", later "ITI Dental Implant System" From the beginning, the first 75 patients have been documented in a prospective case series study, and clinical and radiographic results have been reported at 1-year, 3-years, 5-years and 8-years. The aim of the present study is to examine the long-term outcomes of this original group of patients with at 20 years of clinical function, and to assess the frequency of biological and technical complications during this follow-up period.

NCT ID: NCT00454038 Recruiting - Periimplantitis Clinical Trials

Study of Collagen Membrane in Guided Bone Regeneration

GBR
Start date: June 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The main purpose of this study is to investigate the efficacy of Hypro-Sorb® F, a bilayered bioabsorbable membrane in inducing bone regeneration in different dental procedures requiring GBR.