Clinical Trials Logo

Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT05862129
Other study ID # 2022SF-369
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date May 10, 2023
Est. completion date December 2024

Study information

Verified date May 2023
Source Xi'an Hospital of Traditional Chinese Medicine
Contact Sun Xingwei
Phone +8613571818516
Email 4866442@163.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The goal of this observational study is tolearn the association of gut microflora with the onset of perianal abscesses. The main questions it aims to answer are: Question 1: To understand the structure of rectal microbial community composition and its relationship with pathogenic bacteria in patients with perianal abscess. Question 2: Understand the structure of rectal microbial community composition in healthy people. Participants will be collected with rectal secretions and stool specimens.In addition, patients with perianal abscess should also collect pus samples.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 100
Est. completion date December 2024
Est. primary completion date December 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - Observation group: ? Age between 18-60 years, local resident of Xi'an; ? met the diagnostic criteria for perianal abscess and underwent surgical treatment in our hospital; ? did not use antibiotics before treatment; ? himself and his family members were willing to participate in this study and signed informed consent. Control group: ? Age between 18-60 years, permanent residents in Xi'an; ? had no serious chronic disease, no abnormality in physical examination in the last 1 week; ? did not use drugs that may affect intestinal flora in the last one month; ? himself and his family members are willing to participate in the study and sign the informed consent. Exclusion Criteria: - Failing to retain the specimens as required

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
surgical operation
Radical operation for the perianal abscess

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Xi'an Hospital of Traditional Chinese Medicine

Outcome

Type Measure Description Time frame Safety issue
Primary Observation group: the structure and changes of rectal flora before and after treatment Analysis of the intestinal microflora based on 16S rDNA amplicon sequencing Two months
Primary Control group: the structure and changes of rectal flora in healthy population Analysis of the intestinal microflora based on 16S rDNA amplicon sequencing Two months
See also
  Status Clinical Trial Phase
Active, not recruiting NCT04549311 - Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial Phase 3
Completed NCT01853267 - Perianal Abscess Packing Randomized ControlledTrial Pilot Study N/A
Completed NCT05193032 - Abces After Incision: Recurrence or Not?
Completed NCT04832529 - A Perianal Abscess Cavity Packing vs no Packing. N/A
Completed NCT05529628 - The Immunological Differences Between Fournier Gangrene and Perianal Abscess
Completed NCT02410707 - Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults N/A
Completed NCT03315169 - Packing of Perianal Abscess Cavities N/A
Recruiting NCT05385887 - Antibiotic Treatment foLlowing Surgical drAinage of Perianal abScess; the ATLAS Trial N/A
Recruiting NCT02306382 - Multicenter Study for Diagnosis and Treatment of Perianal Abscesses N/A
Completed NCT00972088 - Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease N/A
Recruiting NCT05990569 - Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia N/A
Recruiting NCT06446635 - Semiflex Assisted Vacuum Therapy for Perianal Abscesses/Sinuses and Fistula: a Pilot Study N/A
Not yet recruiting NCT01739478 - Packing of Perianal Abscess Cavities Trial: A Randomised Multicentre Trial Comparing Packing With Non-packing of the Abscess Cavity N/A