Peri-implant Mucositis Clinical Trial
Official title:
The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy
Peri-implantitis is defined as inflammation in the mucosa surrounding an oral implant with loss of supporting bone. The goals of peri-implantitis treatment are to resolve inflammation and to arrest the progression of disease. It is important to systematically gather information on the effect of surgical peri-implant treatment and to assess different protocols regarding chair-side maintenance of peri-implant tissue after surgery The aims of this clinical investigation are to evaluate the clinical, microbiological and radiographic outcomes of surgical treatment of peri-implantitis and to evaluate the efficacy of 2 supportive treatment protocols based on the use of titanium cyrettes or by the use of a flexible, biodegradable chitosan brush. Furthermore, to evaluate the impact of this therapy on selected biochemical markers associated with chronic inflammation and bone tissue destruction.
Little is known about the effect of chair-side maintenance of dental implants after peri-implantitits surgery. Traditionally, the maintenance has been performed by titanium curettes to remove microbiological deposits from the submucosal area. The Labrida biodegradable brush is a novel debridement device intended for use on dental implants. The concept of using a biodegradable material is related to the suggested problems with leaving remnants on the treated implant surface which would be negative from a bone regenerative aspect. The use of a flexible brush relates to the access problems when treating dental implants both related to the threads as well as due to the prosthetic supra construction hindering access for debridement with regular instruments developed for teeth. The material used in the brush will be Chitosan which is a natural polysaccharide, chitosan (poly-N-acetyl glucosaminoglycan), which is a nontoxic and bioabsorbable (REK-approval 2012/791 polymer). H0: It is possible to maintain peri-implant health after surgical peri-implantitis treatment. There is no short- or long term clinical or radiographical differences between patients surgically treated for peri-implantitis maintained by the use of titanium cyrettes or with the Labrida brush in chair-side supportive care ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05332327 -
Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration
|
||
Enrolling by invitation |
NCT06063876 -
Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
|
N/A | |
Completed |
NCT01941797 -
Experimental Peri-implant Mucositis in Humans
|
N/A | |
Enrolling by invitation |
NCT05675241 -
Characterizing the Inflammation Around Dental Implants
|
||
Completed |
NCT04874467 -
Influence of Keratinized Mucosa on Dental Implants With Mucositis
|
N/A | |
Recruiting |
NCT05906810 -
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
|
N/A | |
Enrolling by invitation |
NCT06137846 -
Treatment of Peri-implant Mucositis and Supportive Peri-implant Therapy
|
N/A | |
Completed |
NCT05945836 -
Peri-implant Disease and Prosthetic Cement: Cross-sectional Study
|
||
Not yet recruiting |
NCT05897736 -
Salivary Minerals in Patients With Peri-implantitis
|
||
Recruiting |
NCT04052373 -
Peri-implantitis Implantoplasty Treatment
|
N/A | |
Completed |
NCT03844035 -
Impacts of Oral Irrigation in Patients With Periimplant Mucositis
|
N/A | |
Completed |
NCT03533166 -
Effects of a 0.03% CHX Mouth Rinse in Peri-implant Mucositis
|
N/A | |
Completed |
NCT03693196 -
The Effect of Different Dental Implant Surface Characteristics on Immunological and Microbiological Parameters
|
N/A | |
Completed |
NCT03998865 -
Bacterial Microbiota Characterization on Implant-supported PEEK and Titanium Provisional Abutments
|
N/A | |
Recruiting |
NCT05592314 -
Lnfluence of the Prosthetic Emergence Profile on the Prevalence of Peri-implant Diseases: a Cross Sectional Study
|
||
Completed |
NCT04899986 -
Chlorhexidine Gel and Peribioma Periogel Use in Peri-implant Mucositis Sites: a Split-mouth Randomized Clinical Trial.
|
N/A | |
Recruiting |
NCT04415801 -
Effect of Repeated Removal and Re-placement of Abutments Around Dental Implants
|
N/A | |
Recruiting |
NCT04283903 -
Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
|
||
Completed |
NCT04215432 -
Propolis Extract, Nanovitamin C and Nanovitamin E in Peri-implant Mucositis
|
N/A | |
Active, not recruiting |
NCT05834946 -
Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis
|
N/A |