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The Management of Perforated Acute Appendicitis in Adult and Pediatric Populations

Perforated Appendicitis Clinical Trial

Official title:
The Management of Perforated Acute Appendicitis: A Randomized Control Trial in the Adult and Pediatric Populations

Clinical Trial Summary

Patients admitted at Marshall Health - Cabell Huntington Hospital with the diagnosis of acute perforated appendicitis or appendicular abscess larger than 3cm will be admitted and treated with percutaneous drainage and the IV antibiotics for 3 days. If the patient becomes afebrile and has a normal WBC, the patient will stay in the hospital for a single day with oral antibiotics and then will be discharged to continue oral antibiotics for seven more days. If the patient is febrile or has elevated WBC either after the 3 days of IV antibiotics or the single day of oral antibiotics, the patient will complete a course of IV antibiotics for a total of seven days. If still febrile, the patient will undergo further assessment. A follow up will be conducted ~10 days after discharge from the hospital to determine if the patient is still symptomatic or asymptomatic. Asymptomatic patients will be followed up every month for 3 months, while symptomatic patients will be treated as needed. After 12 weeks, subjects will be randomized to interval appendectomy vs observation. Follow-ups will occur every 3 months for 12 months, when the study will be concluded.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04253899
Study type Interventional
Source Marshall University
Contact Juan Sanabria, MD MSc FACS
Phone 216 647 8399
Email sanabriaj@marshall.edu
Status Recruiting
Phase N/A
Start date February 20, 2020
Completion date November 2023
View Details
See also
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