The Effect of Gum Chewing on Postoperative Ileus

Perforated Appendicitis Clinical Trial

Official title:

The Effect of Gum Chewing on Postoperative Ileus

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT00879294
• Other study ID #: CR1_IRB00005677
• Status: Withdrawn
• Phase: N/A
• First received: April 9, 2009
• Last updated: November 2, 2017

Study information

• Verified date: July 2017
• Source: Wake Forest University Health Sciences
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to see if chewing gum after surgery for perforated appendicitis will shorten the time of intestinal dysfunction.

Description:

After operations for a ruptured appendix, children are usually not allowed to eat or drink anything. This is because the infection inside the abdomen and the manipulation of the intestines during the operation cause the bowels to stop their normal movement. The resulting lack of bowel function is called an "ileus". When this occurs, intestinal secretions and anything taken in by mouth can become backed up, causing bloating, abdominal pain, nausea and vomiting. Children are not allowed to eat or drink anything during this time and require fluid hydration through an IV or even nutrition through an IV. This ileus usually lasts an average of 4-5 days, and can sometimes delay the discharge of children who are otherwise ready to go. The purpose of this research study is to determine if simple things, like gum chewing or anti-motion sickness bracelets can help speed the time it takes for the bowels to begin working after an operation for a ruptured appendix. Because the gum is not swallowed, it does not have the same effects as eating and drinking would on someone with an ileus. The same is true for the anti-motion sickness bracelets. Yet, it is thought that the chewing action from gum may stimulate the intestines into thinking that food is on the way and cause them to start working sooner than they otherwise might. The same may be true for the bracelets, and some studies show them to be helpful with nausea after surgery. Nevertheless, the effects of a bracelet on postoperative ileus are unproven.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Accepts healthy volunteers: No
• Gender: All
• Age group: 6 Years to 18 Years

Eligibility

Inclusion Criteria:

• any child who has undergone appendectomy for perforated appendicitis

Exclusion Criteria:

• age less than or equal to 5 years

• unable to chew gum safely

• interval appendectomy

Related Conditions & MeSH terms

• Appendicitis
• Perforated Appendicitis

Intervention

Device:
• Motion sickness wristband
No drugs are involved.

Dietary Supplement:
• Chewing Gum
Patients will be asked to chew gum for 20 minutes, four times daily.

Locations

Country	Name	City	State
United States	Brenner Children's Hospital	Winston-Salem	North Carolina

Sponsors (1)

Lead Sponsor	Collaborator
Wake Forest University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time to resolution of post-operative ileus.		1-14 days