The Diagnosis of Beta-lactam Hypersensitivity in Thailand

Status Completed

Clinical Trial Summary

The true prevalence of drug allergy in patients with a history of beta-lactam hypersensitivity will be determined by using commercially available standard skin test reagents and the diagnostic agents available in Thailand. We hypothesize that only minority of patients with such a history are truly allergic.

Clinical Trial Description

Patients with a history of beta-lactam hypersensitivity will be evaluated by the standard skin test reagents (major and minor determinants of penicillin, amoxicillin, and clavulanic if applicable), and intravenous forms of beta-lactam antibiotics .

Diagnostic values of the measurement of specific Immunoglobulin E to penicillin/aminopenicillin and skin test reagents currently available in Thailand will be comparatively analyzed with the standard skin test reagents.

The measurement of drug-induced interferon-gamma releasing cells will be measured in patients with a history of non-immediate reaction. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01667055
Study type	Observational
Source	Chulalongkorn University
Contact
Status	Completed
Phase
Start date	June 2012
Completion date	December 2018

View Details

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