Head Lice Clinical Trial
Official title:
Treatment of Infestation With Pediculus Humanus Capitis in the Community Using a leave-in Spray: A Prospective, Randomised Controlled Study
The purpose of this study is to evaluate the safety and efficacy of Vamousse Spray 'n' Go, compared to a 1% Permethrin control shampoo, in the treatment of head lice.
Effective methods for eradication of lice infestation are available however many are time consuming to use and require diligence; ineffective application of treatments has led to the spread of resistant strains. This is a post-marketing, prospective, open label, randomised controlled study to evaluate the safety and efficacy of Vamousse Spray 'n' Go in subjects infested with Pediculosis Capitis. The product contains a broad spectrum antiparasitic, which may have a unique mode of action, and has a simple and convenient application method. The primary objective of the study will explore whether treatment with Vamousse Spray 'n' Go is more effective in killing lice and eggs compared to a permethrin-based control product. The secondary objective of the study is to demonstrate the safety and local tolerability of Vamousse Spray 'n' Go in children ages 2 years plus. The planned sample size is 58 subjects, equally split between treatment and control groups. Subjects will receive the allocated product on day 0, with follow-up visits on days 2, 7 and 14. A repeat treatment will be administered on day 7 if live lice are still present. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00988533 -
A Pharmacokinetics (PK) Study in Lice Infested Children 6 Months to 3 Years of Age
|
Phase 1 | |
| Completed |
NCT00672971 -
Safety and Efficacy Study to Compare a 4% Dimethicone Foam and Nix Cream Rinse (1% Permethrin) in the Control of Head Lice
|
N/A | |
| Completed |
NCT00858481 -
A Pilot Dose Ranging Study of Spinosad Creme Rinse
|
Phase 2 | |
| Completed |
NCT03301649 -
Clinical Endpoint Study of Ivermectin 0.5% Lotion
|
Phase 3 | |
| Completed |
NCT00994422 -
Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects
|
Phase 2 | |
| Completed |
NCT00995124 -
Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application
|
Phase 4 | |
| Completed |
NCT03337490 -
A Clinical Endpoint Bioequivalence Study to Assess Efficacy and Safety of Ivermectin 0.5% Lotion in the Treatment of Head Lice
|
Phase 3 | |
| Completed |
NCT06333054 -
Safety and Efficacy of a Head Lice Shampoo
|
N/A | |
| Completed |
NCT02213055 -
Pediatric Head Lice Study Product Comparison
|
Phase 2 | |
| Completed |
NCT02974088 -
Neem Lotion With Combing for Lice
|
Phase 2 | |
| Recruiting |
NCT05379114 -
Comparative Study for the Evaluation of a New Medical Device on the Treatment of Head Lice Infestation
|
N/A | |
| Completed |
NCT03617926 -
A Clinical Trial to Evaluate Efficacy and Safety of a Water-soluble Head Lice Product.
|
N/A | |
| Completed |
NCT01803581 -
A Study to Evaluate the Safety and Efficacy of Product X92001327 vs RID Shampoo in Subjects With Head Lice
|
N/A | |
| Completed |
NCT01068158 -
A Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects
|
Phase 3 | |
| Completed |
NCT01066585 -
A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation
|
Phase 3 | |
| Completed |
NCT00857935 -
A Safety and Efficacy Pilot Study Comparing NatrOVA Creme Rinse 1% and NIX Creme Rinse
|
Phase 2 | |
| Completed |
NCT00301340 -
Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice
|
Phase 3 | |
| Completed |
NCT02061813 -
Dermal Safety Study to Evaluate Potential Irritation of Abametapir Lotion
|
Phase 1 | |
| Completed |
NCT02062073 -
Dermal Safety Study to Evaluate the Sensitizing Potential of Abametapir Lotion
|
Phase 1 | |
| Completed |
NCT00605956 -
NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers
|
Phase 1 |