Exercise Intensity and Appetite in Adolescents

Pediatric Obesity Clinical Trial

Official title:

Effect of Acute Exercise Intensity on Energy Intake in Adolescents: Effect of Weight Status

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02484612
• Other study ID #: AME2P Laboratory
• Status: Not yet recruiting
• Phase: N/A
• First received: June 19, 2015
• Last updated: May 10, 2016
• Start date: September 2016
• Est. completion date: December 2017

Study information

• Verified date: May 2016
• Source: Université Blaise Pascal, Clermont-Ferrand
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: National Agency for food Security
• Study type: Interventional

Clinical Trial Summary

Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings.

Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults.

The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.

Description:

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations:

• anthropometric measurements

• Body composition assessed by dual energy x-ray absorptiometry

• Maximal aerobic test

They will then randomly complete the following conditions:

• CON: a control day without exercise;

• HIE: an exercise day with an exercise set at 75% of the capacities

• LIE: an exercise day with an exercise set at 40% of the capacities

The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted.

Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: December 2017
• Est. primary completion date: December 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 12 Years to 15 Years

Eligibility

Inclusion Criteria:

• 12 to 15 years old adolescents

• Obese according to international values for BMI

• Being registered to the national social security insurance

• no eating disorders

• no medications

• metabolic disorders

Exclusion Criteria:

• metabolic disorders

• food disorders

• physical disability

Study Design

Allocation: Randomized, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Pediatric Obesity

Intervention

Behavioral:
• acute exercise

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Université Blaise Pascal, Clermont-Ferrand

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	energy intake in kcal	buffet meal	up to 2 months	No