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Pediatric Disorder clinical trials

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NCT ID: NCT06390007 Not yet recruiting - Pain, Postoperative Clinical Trials

The Efficacy of Acupuncture in the Management of Postoperative Pain in the Pediatric Intensive Care Unit

Start date: May 2024
Phase: N/A
Study type: Interventional

Pain is an unpleasant sensory and emotional experience resulting from tissue damage. Pain management is typically conducted according to the World Health Organization (WHO) pain management ladder. Analgesics administered to pediatric patients vary in dosage and type, but these analgesics often have significant side effects. The acupuncture technique using press needles is a non-pharmacological pain therapy modality that has been studied for its ability to reduce the use of analgesic drugs, thereby potentially decreasing side effects associated with analgesic use. The study was conducted using a randomized controlled trial (RCT) design involving 70 pediatric postoperative patients aged 1-18 years who were admitted to the Pediatric Intensive Care Unit at Cipto Mangunkusumo Hospital. Subjects were divided into two groups: a control group and an experimental group. The control group received standard analgesic therapy and sham press needle application (a patch resembling a press needle without a needle), while the experimental group received standard analgesic therapy and press needle application at acupuncture points after the patient had been in the Pediatric Intensive Care Unit for 24 hours. Pain scale monitoring was conducted at 1, 6, 24, 48, and 72 hours using the Face, Legs, Activity, Cry, and Consolability (FLACC) scale for children aged 1-8 years, and the Numeric Rating Scale (NRS) for children over 8 years old. This study hypothesizes that the acupuncture technique using press needles can reduce the pain scale in pediatric postoperative patients, leading to a decrease in the use of analgesics and a reduction in side effects associated with analgesic use.

NCT ID: NCT06281743 Not yet recruiting - Critical Illness Clinical Trials

Attitudes to Decisions to Withdraw or Withhold Life-sustaining Treatments in Critically Ill Children

LSTPedSurvey
Start date: April 2024
Phase:
Study type: Observational

The aim of this study is to investigate attitudes on decisions to withdraw or withhold life-sustaining treatments in critically ill children in Swedish intensive care units. This is a survey among pediatric critical care physicians.

NCT ID: NCT06053489 Not yet recruiting - Pediatric Disorder Clinical Trials

Effect of Remimazolam and Sevoflurane Anesthesia on Recovery in Pediatric Patients

Start date: June 30, 2024
Phase:
Study type: Observational

The most commonly used anesthetic for general anesthesia in pediatric patients is sevoflurane, an inhalation anesthetic. However, the incidence of emergence agitation after sevoflurane anesthesia in pediatric patients is high, with reports of up to 67%. Remimazolam (Byfavo Inj., Hana Pharm Col, Ltd., Seoul, Korea) has a short context-sensitive half-life of 7.5 minutes, and the time it takes from the end of anesthesia until the patient wakes up is predictable. According to a study by Yang X et al., administering a small amount of remimazolam (0.2 mg/kg) intravenously at the end of general anesthesia using sevoflurane reduced the incidence of emergence agitation. However, very few studies have evaluated the use of remimazolam in general anesthesia in pediatric patients.

NCT ID: NCT05852535 Not yet recruiting - Pediatric Disorder Clinical Trials

Spontaneous Evisceration of Infantile Umbilical Hernia

Start date: May 7, 2023
Phase:
Study type: Observational

Infantile umbilical hernia is common in children. It has a regressive course in most cases. Conservative management is the standard in most cases before the age of 3 years unless there are complications such as incarceration, rupture with evisceration which are extremely rare and warrants emergency surgery. We present a rare case of a 6-month-old child with sudden spontaneous evisceration of infantile umbilical hernia.

NCT ID: NCT04667546 Not yet recruiting - Clinical trials for Urinary Tract Infections

Assessment of the Efficacy on the 5th Day of Antibiotic Therapy for Febrile Urinary Tract Infections Among Children From 3 Months to 18 Years Old

PEDIU5
Start date: December 2020
Phase: N/A
Study type: Interventional

The main objective is to describe the rate of asymptomatic patients after 5 days of effective antibiotic therapy in an uncomplicated febrile urinary tract infection in children between 3 months and 18 years of age.

NCT ID: NCT03880214 Not yet recruiting - Clinical trials for Stem Cell Transplant Complications

Prevalence of Chronic Oral Graft Versus Host Disease Risk Factors in Pediatric Patients

Start date: April 2019
Phase:
Study type: Observational

our aim is estimating the Prevalence and predicting risk factors for developing chronic oral graft versus host disease in pediatric patients subjected to hematopoietic stem cells transplantation

NCT ID: NCT03454152 Not yet recruiting - Pediatric Disorder Clinical Trials

Ecg & Echo Changes in Children With DKA

Start date: March 2019
Phase: N/A
Study type: Observational [Patient Registry]

Diabetic ketoacidosis (DKA) is an important complication of childhood diabetes mellitus and the most frequent diabetes-related cause of death in children. Diabetic ketoacidosis (DKA) is caused by a decrease in effective circulating insulin associated with increases in counter regulatory hormones including glucagon, catecholamines, cortisol, and growth hormone. This leads to increased glucose production by the liver and kidney and impaired peripheral glucose utilisation with resultant hyperglycaemia, and hyperosmolality. Increased lipolysis, with ketone body (beta-hydroxybutyrate, acetoacetate) production causes ketonaemia and metabolic acidosis. Hyperglycaemia and acidosis result in osmotic diuresis, dehydration, and obligate loss of electrolytes.