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NCT03527979 Clinical Trial

Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome

PCOS Clinical Trial

Official title:
Effect of Laparoscopic Ovarian Drilling on the Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03527979
Other study ID # rkamal
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date March 1, 2018
Est. completion date September 2018

Study information
Verified date May 2018
Source Ain Shams University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

the polycystic ovarian syndrome is associated with an ovulation and infertility. recently the laparoscopic ovarian drilling has been used as surgical treatment for ovulation in women with polycystic ovarian syndrome, although its mechanism and outcomes are still unclear. this study is undertaken to evaluate the in vitro fertilisation outcomes in clomiphene-resistant women with PCOS who were treated with LOD.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 88
Est. completion date September 2018
Est. primary completion date August 2018
Accepts healthy volunteers No
Gender Female
Age group 25 Years to 35 Years
Eligibility Inclusion Criteria:

- age between 25 and 35

- patients with established PCOS

- history at least one year infertility

- no response to clomiphene citrate for at least three cycles

Exclusion Criteria:

- history of previous IVF/ICSI

- chronic disease such as thyroid disorder and DM

- infertility due to sever male factor

- sever endometriosis

- infertility due to uterine factor such as multiple fibroid

- body mass index > 30

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• IVF/ICSI
IVF/ICSI

Locations
Country Name City State
Egypt Ain Shams university Cairo

Sponsors (1)
Lead Sponsor Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary clinical pregnancy rate confirmed by b-hcg and visualizations of gestational sac by ultrasound Pregnancy confirmed by b-hcg and visualization of gestational sac by ultrasound 3 months
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