Clinical Trials Logo

Clinical Trial Summary

The goal of the proposed study is to evaluate the efficacy and safety of the drug memantine in individuals with pathological gambling (PG). Thirty subjects with DSM-IV PG will receive 10 weeks of open-label treatment with memantine. The hypothesis to be tested is that memantine will be effective and well tolerated in patients with PG. We hypothesize that memantine will reduce the severity of gambling symptoms and improve patients' overall functioning. This study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.


Clinical Trial Description

n/a


Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00585169
Study type Interventional
Source Yale University
Contact
Status Completed
Phase Phase 2
Start date December 2007
Completion date December 2011

See also
  Status Clinical Trial Phase
Completed NCT02590211 - Poker, Skills and Associated Problems N/A
Completed NCT02203786 - D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement Phase 2
Completed NCT05051085 - Feasibility of the Internet-delivered Treatment "SpilleFri" for Patients With Pathological Gambling N/A
Completed NCT01215357 - Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble Phase 2
Terminated NCT00245583 - Topiramate in the Treatment of Pathological Gambling Phase 3
Completed NCT04842461 - Mental Health, Addictions and Biomarkers in High Athletes Performance
Not yet recruiting NCT03280966 - Effects of Intranasal Naloxone on Gambling Urges in Gambling Disorder Phase 2
Active, not recruiting NCT01743092 - Testing Resources: Manual and Webinar Guided Treatment vs. Manual Guided Treatment N/A
Active, not recruiting NCT01528982 - Susceptibility to Pathological Gambling N/A
Terminated NCT00211822 - Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD) N/A
Completed NCT01381250 - Effects of Internet-based Treatment of Pathological Gambling N/A
Completed NCT05506384 - Treatment Study for Problematic Gaming and Gambling N/A
Enrolling by invitation NCT03464838 - Effects of Transcranial Direct Current Stimulation (tDCS) in Gambling Disorder N/A
Terminated NCT01560351 - Repeated Low-frequency Transcranial Magnetic Stimulation Reduces Cue-induced Craving: a Randomized, Prospective, Double-blind, Sham-controlled, Cross-over Study N/A
Completed NCT00580567 - Impulsivity in Pathological Gambling N/A
Completed NCT02240485 - Integrative Couple Treatment for Pathological Gambling N/A
Withdrawn NCT01340274 - Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling Phase 2
Recruiting NCT02491996 - The Efficacy of Therapy Focused on Desire-satisfaction for Disordered Gamblers N/A
Recruiting NCT01154712 - Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for Cessation of Pathological Gambling Phase 1
Completed NCT01843699 - Topiramate Trial for Pathological Gamblers Phase 2