Pathological Gambling Clinical Trial
Official title:
Bupropion Versus Placebo in the Treatment of Pathological Gambling
Verified date | March 2017 |
Source | University of Iowa |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will determine whether the drug bupropion is an effective treatment for Pathological Gambling.
Status | Completed |
Enrollment | 80 |
Est. completion date | April 2006 |
Est. primary completion date | May 2005 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Meet the criteria for Pathological Gambling (DSM-IV-TR), through the administration of the National Opinion Research Center DSM Screen for Gambling Problems(NODS); - Meet the criteria for Pathological Gambling (DSM-IV-TR), through the administration of the National Opinion Research Center DSM Screen for Gambling Problems(NODS); - Receive a score of 5 or more on the South Oaks Gambling Screen (SOGS); - Have PG for at least one year; - Have had at least 2 or more gambling episodes during the 2-week screening period; - Speak standard English; - Be able to give written informed consent. Exclusion Criteria: - Evidence of current (past 3 months) substance misuse; - Had a Hamilton Depression Rating Scale (HDRS)27 score of 18 or more (or a score on item 1 of greater than 2; - Had a current eating disorder (except binge eating disorder); - Had any history of seizures, or suicidal or aggressive behavior; - Had a urine drug screen positive for stimulants, opiates, hallucinogens, or phencyclidine; - Had a current or past psychotic disorder, bipolar disorder, or significant cognitive disorder; - Received monoamine oxidase inhibitors within 3 weeks of randomization, long acting phenothiazine within 3 months of randomization,fluoxetine within 4 weeks of randomization, or other psychotropic drugs within 2 weeks of randomization; - Had prior exposure to bupropion; - Were engaged in individual, group, or couples psychotherapy during the 2 weeks before randomization, (except Gamblers Anonymous). |
Country | Name | City | State |
---|---|---|---|
United States | Roy J. and Lucille A. Carver College of Medicine, University of Iowa | Iowa City | Iowa |
Lead Sponsor | Collaborator |
---|---|
University of Iowa | National Institute of Mental Health (NIMH) |
United States,
Black DW, Arndt S, Coryell WH, Argo T, Forbush KT, Shaw MC, Perry P, Allen J. Bupropion in the treatment of pathological gambling: a randomized, double-blind, placebo-controlled, flexible-dose study. J Clin Psychopharmacol. 2007 Apr;27(2):143-50. — View Citation
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