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Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants

Patent Ductus Arteriosus Clinical Trial

Official title:
Changes of Cerebral Tissue Oxygen Saturation During Treatment of Patent Ductus Arteriosus in Neonates

Clinical Trial Summary

The purpose of this study is to examine the influence medical or surgical treatment for patent ductus arteriosus in preterm infants on cerebral and renal tissue oxygenation and on cardiac output.

Clinical Trial Description

In this observational trial the investigators want to examine whether clinical or echocardiographic parameters of patent ductus arteriosus are related to

- cerebral tissue oxygen saturation, total hemoglobin, fractional tissue oxygen extraction and HbD

- renal tissue oxygen saturation, total hemoglobin, fractional tissue oxygen extraction and HbD

as measured by near infrared spectroscopy

and to

- stroke volume

- cardiac output

as measured by electrical cardiometry.

The investigators want to examine the impact of surgical and medical treatment for patent ductus on these parameters. The investigators want to compare the change of these parameters between responders to medical treatment and nonresponders. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01428180
Study type Observational
Source University of Ulm
Contact
Status Completed
Phase Phase 4
Start date April 2011
Completion date March 2016
View Details
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