Endovascular Function in Atrial Fibrillation (AF) Patients

PAT Result Clinical Trial

— HEAF  

Official title:

Endovascular Function in Patients With Atrial Fibrillation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02062957
• Other study ID #: NF81300148
• Status: Recruiting
• Phase: N/A
• First received: February 11, 2014
• Last updated: February 23, 2014
• Start date: February 2014

Study information

• Verified date: February 2014
• Source: Beijing Chao Yang Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Beijing Municipal Science and Technology Commission
• Study type: Observational

Clinical Trial Summary

1. recruit 50 patients with atrial fibrillation and 30 controls

2. endovascular function assessment with Peripheral Arterial Tonometry (PAT)

3. follow up the occurence of AF

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 80
• Est. primary completion date: July 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• =2 paroxysmal (electrocardiographic documentation of at least 1) AF episodes lasting =1 hour in duration: (that terminate spontaneously within 7 days or cardioversion is performed within 48h of AF onset): or

• electrocardiographic documentation of 1 persistent AF episode: (sustained for =7 days or cardioversion is performed more than 48h after AF onset): or

• electrocardiographic documentation of 1 longstanding persistent AF episode:

(continuous AF of duration >1 year).

Exclusion Criteria:

• patients with cerebralvascular disease

• patients with coronary disease

• patients with peripheric artery disease

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Atrial Fibrillation
• PAT Result

Locations

Country	Name	City	State
China	Beijing Chaoyang Hospital	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Beijing Chao Yang Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	endovascular function results	The method to assess the endovascular function is PAT. The index is Reactive hyperemia index (RHI). RHI between patients and control will be compared.	Up to 24 weeks.	No
Secondary	predictive effect of endovascular function on recurrence of AF	We will do the multi-logistic analysis of the recurrence of AF.	Up to 1 year	No