Zirconia Implants for Replacement of a Single Tooth

Status Active, not recruiting

Clinical Trial Summary

First, the surgical insertion of a ceramic (zirconia) dental implant will be performed in a single-tooth gap according to current state-of-the-art protocols. After a 3-months healing phase, a ceramic tooth replacement (a.k.a. implant crown) will be screw-retained on the implant and will be ready for full chewing, aesthetic and speech function.

Clinical Trial Description

Surgery Implant placement will be performed according to a standardized, well-documented surgical protocol considered internationally as state-of-the art therapy for titanium implants since decades (Buser & von Arx 2000, Buser et al. 2004). In summary, an osteotomy will be performed in the edentulous bone under local anaesthesia and after the elevation of a full-thickness mucoperiosteal flap. The screw-shaped implant will then be inserted into the osteotomy. Particular emphasis will be set on risk minimization for adjacent anatomical structures (e.g. nerves, adjacent teeth), on sufficient primary implant stability, on circular embedding in > 1 mm thick bone walls and on correct three-dimensional implant positioning. In cases with insufficient bone volume, guided bone regeneration (GBR) will be performed using autogenous bone chips from the adjacent area, well-documented bovine bone mineral and resorbable porcine collagen membranes. The flaps will then be sutured around the implant healing cap (non-submerged healing). Primary flap closure will be preferred in cases with GBR (submerged healing). 12 ± 2 weeks after placement, submerged implants will be uncovered under local anaesthesia, then the osseointegration of the implants will be verified clinically and radiographically, and impressions will be taken. Restoration Restoration in group A (tooth replacement in FDI positions 14 - 24): fixed implant-supported provisional for 3 months, then final restoration with all-ceramic screw-retained single implant-supported crown (abutment made of zirconium dioxide and crown finalized with hand-build up ceramic veneering material) Restoration in group B (tooth replacement in all other positions): all-ceramic screw-retained single implant-supported crown (abutment made of zirconium dioxide and monolithic lithium disilicate ceramic crown. ;

Study Design

Related Conditions & MeSH terms

Partial-edentulism

Clinical Trial Details

NCT number	NCT04695899
Study type	Observational
Source	University of Bern
Contact
Status	Active, not recruiting
Phase
Start date	March 1, 2017
Completion date	February 28, 2030

View Details

See also
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Active, not recruiting	`NCT04929743` - Randomized Clinical Trial to Evaluate the Predictability of 5.5 mm Dental Implants	N/A
Active, not recruiting	`NCT04927819` - Extra-short vs. Non-extra-short Dental Implants Splinted on the Same Prosthesis
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Recruiting	`NCT05583123` - One-piece and Two-piece Zirconia Abutments in Single Implant Crowns in Esthetic Region	N/A
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Not yet recruiting	`NCT06056388` - Effect of Fixture Thread Depth on Accuracy of Immediate Implant Placement Using Dynamic Navigation	N/A
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Not yet recruiting	`NCT04895969` - Prevalence of Partial Edentulism Among Patients of Faculty of Dentistry Cairo University

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.