Chronic Presence of Epstein Barr Virus in Sulcular and Junctional Epithelial Tissue From Gingiva is Associated With Severe Periodontitis

Parodontitis Aggressive Clinical Trial

Status Recruiting

Clinical Trial Summary

The etiopathogenesis of periodontal disease results from complex interaction between infectious agents, mainly including bacteria, and host cellular and humoral immune responses. However it is thought that bacteria-induced pathogenesis is not sufficient alone to explain all biological and clinical features of the destructive periodontal disease. The main hypothesis is that herpesviruses, such as Epstein-Barr Virus, may participate as well by altering epithelial gingival cell biology and consequently may promote the initiation and progression of periodontitis.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Parodontitis Aggressive
• Parodontitis Chronic
• Periodontitis

• NCT number: NCT01246648
• Study type: Interventional
• Source: Centre Hospitalier Universitaire de Nice
• Contact: OLIVERI Vanina, ARC promoteur
• Phone: 0033 4 92 03 42 54
• Email: oliveri.v@chu-nice.fr
• Status: Recruiting
• Phase: N/A
• Start date: January 2011
• Completion date: January 2013