Parkinson Clinical Trial
Official title:
Pilot Study for Development of a Monitoring Set-up and Algorithm Using Functional MRI (fMRI) and EEG for Prediction of Response to Repetitive Deep Transcranial Magnetic Stimulation (rDTMS) for Patients With Parkinson's Disease
- To characterize physiological biomarkers of positive response to rDTMS using EEG and
functional MRI (fMRI) in patients with PD.
- To develop a set-up and algorithm for neurophysiological monitoring for PD patients
using EEG and fMRI in patients treated by rDTMS.
- To integrate rDTMS stimulation with monitoring techniques with the ultimate goal of
providing closed-loop feedback where monitoring informs the stimulation
PD Patients aged 40 years or older, diagnosed as idiopathic PD according to the UK Brain Bank criteria will be treated by an established rDTMS protocol will be monitored before, during and after rDTMS using quantitative EEG and brain network analysis and fMRI while performing a series of cognitive and motor tasks. ;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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