Exercise Intervention and Dexterity in Parkinson

Parkinson Clinical Trial

Official title:

Therapeutic Intervention in Motor Disorders in Parkinson.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01749917
• Other study ID #: DF0036UG
• Status: Completed
• Phase: N/A
• First received: December 12, 2012
• Last updated: November 1, 2016
• Start date: December 2012
• Est. completion date: February 2015

Study information

• Verified date: November 2016
• Source: Universidad de Granada
• Contact: n/a
• Is FDA regulated: No
• Health authority: Spain: Comité Ético de Investigación Clínica
• Study type: Interventional

Clinical Trial Summary

The investigators conducted an intervention based in proprioceptive exercises and balance tasks. The investigators also carried out a brief intervention in manual dexterity.

The study hypothesis is that a brief intervention in upper extremities and a exercise program can increase functionality in Parkinson.

Description:

Motor symptoms in Parkinson frequently affect upper extremities. This has been associated in previous studies with limitation in the performance of activities of daily living and, consequently, with a decrease in quality of life. The possibility that a brief intervention improves eye-hand dexterity in Parkinson's, may be a therapeutic option to improve the performance of activities of daily living. The investigators also conducted an intervention based in proprioceptive exercises and balance tasks to improve functionality.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: February 2015
• Est. primary completion date: December 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 40 Years to 65 Years

Eligibility

Inclusion Criteria:

• Subjects diagnosed with Parkinson attending to the Parkinson Association of Granada.

• Subjects who can complete the assessment battery of tests at the beginning and at the end of the study.

Exclusion Criteria:

• Auditive and visual disturbances.

• Cognitive problems.

• Psychiatric pathology.

• Sensorial disturbances.

• Traumatic pathology of the hand.

• Concomitant neurological conditions.

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Parkinson
• Parkinson Disease

Intervention

Other:
• Exercise program
Exercise program An brief exercise session including proprioceptive and dexterity activities
• Control intervention
Active upper limb range of movement exercises for 15 minutes.

Locations

Country	Name	City	State
Spain	Faculty of Health Sciences. University of Granada.	Granada	Andalucia

Sponsors (1)

Lead Sponsor	Collaborator
Universidad de Granada

Country where clinical trial is conducted

Spain, 

References & Publications (1)

Mateos-Toset S, Cabrera-Martos I, Torres-Sánchez I, Ortiz-Rubio A, González-Jiménez E, Valenza MC. Effects of a Single Hand-Exercise Session on Manual Dexterity and Strength in Persons with Parkinson Disease: A Randomized Controlled Trial. PM R. 2016 Feb;8(2):115-22. doi: 10.1016/j.pmrj.2015.06.004. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Manual dexterity	Change from baseline to postintervention in dexterity. This is assessed using the Purdue Pegboard Test.; The Purdue pegboard test is a timed physical test used to measure manual dexterity. Test subjects are asked to place small pins into holes in the pegboard using a specific hand and following a specific process.	baseline, 6 months	Yes
Secondary	Grip strength	Grip strength is measured using a Jamar dynamometer with a standard protocol allowing three attempts on each side. During each measurement, patients were sitting with their shoulder adducted and elbow flexed to 90°. The maximum value achieved from all six attempts was used in analyses.; Kg/cm2	baseline, 6 months	Yes
Secondary	Pressure pain measure	The pressure pain threshold for each site (three points in upper extremities) is assessed using the pressure algometer. All assessments were made by the same investigator. All the subjects were trained to familiarize the subjects with the pressure algometry procedure before the measures in an anatomical site different from the chosen sites for this study.	baseline, 6 months.	Yes
Secondary	Nervous assessment	Neurodynamic tests are used in upper extremities. It moves most of the nerves between the neck and hand, including the median nerve, radial and ulnar, brachial plexus, spinal nerves and cervical nerve roots.; The patient is placed supine position. It is measured with a goniometer.	baseline, 6 months.	Yes
Secondary	Risk of falls.	The risk of falls is measured with the timed up and go. It measures in seconds, the time taken by an individual to stand up from a standard arm chair,walk a distance of 3 meters, turn, walk back to the chair, and sit down.	baseline, 6 months.	Yes