Clinical Trials Logo

Clinical Trial Summary

To develop a tissue bank library for patients with parathyroid disease who have undergone surgery and/or biopsy, and/or who may undergo surgical intervention at M. D. Anderson Cancer Center or outside centers, and/or all patients seen through the Parathyroid Center at participating sites, whether or not the patients undergo treatment for their disease. The tissue bank will contain both normal parathyroid tissue and diseased tissue, and will provide a resource for the ongoing study of parathyroid disease and management.


Clinical Trial Description

Fresh residual tissue samples will be obtained during parathyroid and/or pancreas tumor intervention (for pancreas tumor intervention in MEN1 patients with hyperparathyroidism and pancreatic lesions).

In addition, outside paraffin tissue blocks or slides will be requested from patients presenting to MDACC, or to participating family members who have had prior surgery outside of MD Anderson.

Forty cubic centimeters (40 ccs) of whole blood will be obtained from individuals for peripheral blood lymphocyte, plasma, and serum separation and analysis per event. Collections may be made at any or all of the following timepoints: preoperatively, during intervention, and/or at subsequent follow-up visits for up to fifteen years. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03051126
Study type Observational
Source M.D. Anderson Cancer Center
Contact Nancy D. Perrier, MD
Phone 713-792-6940
Email NPerrier@mdanderson.org
Status Recruiting
Phase
Start date July 9, 2009
Completion date July 1, 2025

See also
  Status Clinical Trial Phase
Terminated NCT03044600 - Gene Expression in Hyperparathyroidism
Completed NCT01805856 - Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery N/A
Completed NCT01794676 - Genetic Evaluation of Families With Endocrine Cancers N/A
Completed NCT01545622 - Surgeon Compared to Nuclear Radiology Readers for Tc-99m Sestamibi Scans for Parathyroid Disease N/A
Withdrawn NCT00528502 - Lidocaine Supplement for Minimal Invasive Parathyroid Surgery Phase 3
Completed NCT01539486 - Relationship of Preoperative Parathyroid Hormone (PTH) and Ex-Vivo Gamma Counts in Minimally Invasive Parathyroidectomy
Completed NCT01539499 - Complications of Endocrine Surgery: Data From the United HealthSystem Consortium N/A
Completed NCT01574287 - Anti-3-[18F]FACBC Imaging of Parathyroid Adenomas N/A