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Papillary Thyroid Carcinoma clinical trials

View clinical trials related to Papillary Thyroid Carcinoma.

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NCT ID: NCT03411187 Recruiting - Thyroid Cancer Clinical Trials

Study on the Application of Convenient Foot-control Exhaust Method in Endoscopic Thyroidectomy

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Endoscopic thyroidectomy developed rapidly in recent years, and the most popular surgical approach was endoscopic thyroidectomy by bilateral areola approach, but some operative steps was required optimization. One of the most annoying problem was the smog blurring endoscopic lens during surgery. The researcher summarized a set of convenient foot-control exhaust method and carried out this prospective study.

NCT ID: NCT02814032 Recruiting - Clinical trials for Papillary Thyroid Carcinoma

Proteomics of Papillary Thyroid Carcinoma

Start date: June 2016
Phase:
Study type: Observational

Thyroid carcinoma is the common endocrine system malignant neoplasm. At present it has become the malignant neoplasm of fastest growing incidence rate. More than 85% thyroid carcinoma is papillary thyroid carcinoma. Cervical lymph node metastasis is common in papillary thyroid carcinoma patients. This study aim to reveal protein expression differences between papillary thyroid carcinoma with cervical lymph node metastasis and without cervical lymph node metastasis.

NCT ID: NCT02561533 Completed - Clinical trials for Papillary Thyroid Carcinoma

Detection of BRAF Mutation on FNAB From Papillary Thyroid Carcinoma

Start date: December 2014
Phase: N/A
Study type: Interventional

Immunohistochemical detection of the BRAF-V600E mutation on pre-operative fine needle aspiration biopsy (FNAB) from patients suspected for papillary thyroid carcinoma, using the mutation specific antibody VE1.

NCT ID: NCT02323724 Completed - Clinical trials for Papillary Thyroid Carcinoma

APPLICATION OF MOLECULAR TECHNIQUES FOR IMPROVING THE DIAGNOSIS AND TREATMENT OF NODULAR THYROID LESIONS.

Start date: February 2015
Phase: N/A
Study type: Observational

To determine the improvement in diagnosis of papillary carcinoma by detecting mutation V600E BRAF in retrospective cases with inconclusive cytologic diagnosis (categories III, IV and V of Bethesda System)

NCT ID: NCT01534897 Completed - Clinical trials for Papillary Thyroid Carcinoma

Re-differentiation of Radioiodine-Refractory BRAF V600E-mutant Papillary Thyroid Carcinoma With GSK2118436

Start date: July 2012
Phase: N/A
Study type: Interventional

Radioactive iodine therapy is often part of the standard treatment for Papillary Thyroid Carcinoma (PTC) patients. However, in many patients, tumors develop a resistance or no longer respond to radioactive iodine therapy (iodine-refractory). Several lines of evidence suggest that blocking the BRAF gene may help to re-sensitize the tumors to radioactive iodine. BRAF is a protein that plays a central role in the growth and survival of cancer cells in some types of PTC. The investigational drug GSK2118436 may work by blocking the BRAF protein in cancer cells lines and tumors that have a mutated BRAF gene. In this research study, the investigators are looking to see if GSK2118436 can re-sensitize iodine-refractory PTC to radioactive iodine therapy. The investigators are also looking at the safety of adding GSK2118436 to radioactive iodine therapy.

NCT ID: NCT01417442 Recruiting - Clinical trials for Papillary Thyroid Carcinoma

BRAF V600E Mutations In Papillary Thyroid Carcinoma

Start date: July 2011
Phase: Phase 0
Study type: Interventional

The purpose of this study is to determine whether BRAF V600E mutation in our patients with papillary thyroid cancer has an association with poor prognosis.

NCT ID: NCT01354639 Completed - Clinical trials for Papillary Thyroid Carcinoma

Comparative Study of Surgical Completeness After Robotic Thyroidectomy Versus Conventional Open Thyroidectomy

Start date: April 2011
Phase: N/A
Study type: Observational

The robotic thyroidectomy (RT) has excellent cosmetic and several functional results. But there were no definite evidence of oncological safety of robotic thyroidectomy yet. To assure the surgical completeness of robotic thyroidectomy, the investigators compared robotic thyroidectomy and conventional open thyroidectomy (OT) by means of the postoperative radioactive iodine (RAI) uptake of possible remnant thyroid tissue and stimulated TG level.

NCT ID: NCT01311089 Completed - Clinical trials for Papillary Thyroid Carcinoma

A Comparative Study of Robotic Thyroidectomy Using Transaxillary Approach Versus Conventional Open Thyroidectomy

Start date: January 2011
Phase: N/A
Study type: Observational

Most patients with thyroid tumors are effectively treated surgically by practitioners experienced in the techniques of thyroidectomy. Many patients, especially women, undergoing thyroid surgery are concerned about the postoperative cosmetic appearance of the neck. Robotic thyroidectomy which can hide the operative scar was associated with a higher degree of patient cosmetic satisfaction.