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NCT04076514 Clinical Trial

The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma

Papillary Thyroid Cancer Clinical Trial

— pCND  

Official title:
The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04076514
Other study ID # Ahmed1712
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date September 1, 2020
Est. completion date November 1, 2020

Study information
Verified date July 2020
Source Assiut University
Contact ahmed kamel ali
Phone 00201021259455
Email ahmed01155@med.aun.edu.eg
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The benefits of prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC). This study main goal is to investigate benefits of prophylactic central neck dissection in clinically node-negative papillary thyroid carcinoma.

Description:

Papillary thyroid carcinoma (PTC) is the most common type of differentiated thyroid carcinoma. Recurrence rate is still high. The standard management is total thyroidectomy. regional lymph node metastasis is noted in recurrent cases. Some studies stated benefits of central neck dissection in orevention of recurrence and others said there is no benefits. so prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC).

Recruitment information / eligibility
Status Recruiting
Enrollment 20
Est. completion date November 1, 2020
Est. primary completion date September 30, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 16 Years and older
Eligibility Inclusion Criteria:

- patients with papillary thyroid cancer with clinically node negative.

Exclusion Criteria:

- patients with clinical evidence of nodal metastases.

- patients with a previous history of thyroidectomy.

- patients with mixed-type papillary thyroid cancer.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• central neck dissection
dissection of central cervical lymph node grope in low grade papillary thyroid cancer

Locations
Country Name City State
Egypt Ahmed Kamel Asyut Asyut

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary the incidence metastatic lymph node in patients with clinically node-negative thyroid carcinoma who underwent total thyroidectomy with central neck dissection numbers of positive histopathological lymph node biopsies postoperative 12 months
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