Disruption of Memory Reconsolidating as a Treatment for Panic Disorder

Status Not yet recruiting

Clinical Trial Summary

Animal and human fear conditioning studies have repeatedly shown that administering propranolol before or after retrieval of a previously acquired fear results in an elimination of the fear expression. This approach, known as disruption of fear memory reconsolidation, is a promising new avenue for treating anxiety disorders. The present study aims to test its efficacy in patients with panic disorder.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Panic Disorder

Clinical Trial Details

NCT number	NCT02631694
Study type	Interventional
Source	VU University of Amsterdam
Contact	Arnold A.P. van Emmerik, PhD
Phone	0031205258604
Email	A.A.P.vanEmmerik@uva.nl
Status	Not yet recruiting
Phase	Phase 2
Start date	April 2016
Completion date	September 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05868135` - Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological Treatment
Active, not recruiting	`NCT05530642` - An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel	N/A
Completed	`NCT02998502` - The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens	N/A
Completed	`NCT01955954` - Using the Canary Breathing System for Panic Disorder Patients	N/A
Completed	`NCT01963806` - ACT-smart: Smartphone-supplemented iCBT for Social Phobia and/or Panic Disorder	N/A
Completed	`NCT01201967` - A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients	Phase 4
Completed	`NCT00711737` - Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months	N/A
Completed	`NCT00525226` - Evaluating the Effects of Stress in Pregnancy	N/A
Completed	`NCT00605813` - Special Investigation Of Long Term Use Of Sertraline.
Completed	`NCT00353470` - Comparison of Psychotherapy Programs to Treat Panic Disorder	Phase 3
Completed	`NCT00167479` - A Study of Risperidone Monotherapy in Bipolar Anxiety	Phase 4
Completed	`NCT00540098` - Paroxetine vs Placebo Combined With Aerobic Exercise or Relaxation in Panic Disorder	Phase 4
Completed	`NCT03233542` - The Association Between Physical Sensations and Thinking Styles	N/A
Recruiting	`NCT05967468` - Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder	N/A
Completed	`NCT02811458` - Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety Disorders	N/A
Active, not recruiting	`NCT05124639` - Clinical Trial of a Group Self-management Support Program for Anxiety Disorders	N/A
Completed	`NCT04592536` - A Trial of the Effect of CVL-865 on Panic Symptoms Induced by Carbon Dioxide Inhalation in Healthy Subjects	Phase 1
Completed	`NCT00025974` - Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder	N/A
Recruiting	`NCT02305537` - Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment	N/A
Terminated	`NCT01680107` - D-cycloserine Augmented CBT for Panic Disorder	Phase 3