Pancreatic Neoplasm Clinical Trial
Official title:
Comparative Evaluation of the Diagnostic Yield and Sample Quality in Endoscopic Ultrasound(EUS)-Guided Fine Needle Biopsy(FNB) of Pancreatic Solid Lesions With and Without Syringe Suction
Tissue acquisition by Endoscopic Ultrasound (EUS) has become a modality of diagnosis and
clinical orientation for several diseases. Although tissue acquisition traditionally involves
the cytological diagnosis (using fine-needle aspiration/FNA), the importance of obtaining a
core for histological examination (by fine-needle biopsy/FNB) has recently been recognized.
Currently, there is no clear establishment of the usefulness of syringe suction for the
diagnostic accuracy of solid pancreatic lesions when FNB is used.
Because of that, the investigators aimed to compare sensitivity, sample adequacy, and
diagnostic yield of solid pancreatic lesions EUS-guided sampling using with and without
syringe suction.
The study will be conducted on a consecutive sample of patients proposed to perform EUS for
solid pancreatic lesions characterization, in which the clinical and imaging findings justify
the need for an FNB.
For each case, FNB will be performed using two punctures: one with 20mL syringe suction, and
another without suction. The order in which they will be performed will be known only by the
performing physician and the nursing team at the time that FNB is proposed. This information
will be concealed from the pathologist responsible for sample analysis.
Clinical care during and after the procedure will follow the existing guidelines.
Participants will undergo a single clinical evaluation (at the time of endoscopy and
recovery) without the need for follow-up visits.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01354795 -
Prospective Study Comparing Methods of Obtainment of Specimen After EUS-FNA in Patients With Peri-pancreatic Mass
|
N/A | |
Completed |
NCT00958841 -
Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin
|
Phase 2 | |
Terminated |
NCT00249301 -
A Study of MLN8054 in Patients With Advanced Solid Tumors
|
Phase 1 | |
Recruiting |
NCT06122896 -
Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals
|
Early Phase 1 | |
Terminated |
NCT02602067 -
131Iodine-Tenatumomab Treatment in Tenascin-C Positive Cancer Patients
|
Phase 1 | |
Recruiting |
NCT06411795 -
Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
|
Phase 2 | |
Completed |
NCT03622229 -
EUS-FNB for Solid Pancreatic Lesions: Side-fenestrated Vs Fork-tip Needle
|
N/A | |
Recruiting |
NCT06400472 -
A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
|
Phase 1 | |
Completed |
NCT02791503 -
CROSSFIRE Trial: Comparing the Efficacy of Irreversible Electroporation With Radiotherapy
|
N/A | |
Recruiting |
NCT05786716 -
DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations
|
Phase 2/Phase 3 | |
Completed |
NCT03322592 -
EUS-FNB With ROSE Vs. EUS-FNB Without ROSE
|
N/A | |
Completed |
NCT05745415 -
Cancer Stem Cell Specific Aptamer's Ability to Detect Blood Circulating Cancer Stem Cells and Its Role as a Predictor of Prognosis in Pancreatic Cancer
|
||
Recruiting |
NCT05083247 -
Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma
|
Phase 2 | |
Completed |
NCT00436423 -
A Phase Ⅱ Study of Gemcitabine Combination With TS-1 in Patient With Advanced or Recurred Pancreatic Cancer
|
Phase 2 | |
Completed |
NCT02900950 -
Multicolour Versus Monocolour Specimens Inking After Pancreaticoduodenectomy for Periampullary Cancer
|
N/A | |
Completed |
NCT00711191 -
A Study On An Immunostimulant Antibody In Combination With Chemotherapy For Advanced Cancer Of The Pancreas
|
Phase 1 | |
Completed |
NCT00222898 -
Cancer Detection in Pancreatic Cysts
|
N/A | |
Completed |
NCT00034281 -
Safety and Tolerability Study of TAK-165 in Subjects With Tumors Expressing HER2
|
Phase 1 | |
Completed |
NCT00005926 -
Gemcitabine, Herceptin and Radiation to Treat Cancer of the Pancreas
|
Phase 2 | |
Recruiting |
NCT05687123 -
Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors
|
Phase 1 |