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Targeting Pancreatic Cancer With Sodium Glucose Transporter 2 (SGLT2) Inhibition

Pancreatic Cancer Clinical Trial

Official title:
Targeting Pancreatic Cancer With Sodium Glucose Transporter 2 (SGLT2) Inhibition

Clinical Trial Summary

This is a first-in-human, pilot study of the feasibility and safety of dapagliflozin (in addition to standard of care treatment) for the treatment of patients with metastatic pancreatic ductal adenocarcinoma. The primary hypothesis is that dapagliflozin is well-tolerated and safe to use in this patient population. The investigators also hypothesize that dapagliflozin will be efficacious as an adjunct to front-line chemotherapy assessed by decreased tumor markers mediated by its pleiotropic metabolic effects.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04542291
Study type Interventional
Source Washington University School of Medicine
Contact
Status Completed
Phase Phase 1
Start date February 25, 2021
Completion date January 19, 2022
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