Pancreatic Cancer Clinical Trial
— UCSF PCROfficial title:
Population-Based Analysis of Neoplastic Changes in Cystic Lesions of the Pancreas.
NCT number | NCT04291651 |
Other study ID # | 214521 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | October 8, 2019 |
Est. completion date | January 1, 2030 |
Pancreatic cysts are found incidentally on 15-50% of CT and MRIs for all indications and their prevalence is increasing. Many of these cysts may be precursors to pancreatic cancer, and thus pose a substantial risk, however, the vast majority are benign. Increased detection of pancreatic cysts provides an opportunity to diagnose pancreatic malignancy at an early, curable stage yet also increases the potential to over-treat clinically insignificant lesions. This presents a clinical challenge to prevent unnecessary resection of indolent disease, with associated risks of infections, bleeding, diabetes, and costly disability. Unfortunately, there is little information on the epidemiology and natural history of pancreatic cysts to help guide management.
Status | Recruiting |
Enrollment | 4000 |
Est. completion date | January 1, 2030 |
Est. primary completion date | January 1, 2030 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - The inclusion criteria for this study are intentionally broad. Eligible patients for prospective enrollment will include - Adults = 30 years of age - Have a radiographic or endoscopic diagnosis of at least one pancreatic cysts regardless of treatment status, - No history of pancreatic cancer, - Can speak and read English, - Have access to a computer or mobile device (~95% of U.S. population); and - Are able to complete an electronic informed consent. Exclusion Criteria: - Patients who don't speak English, - Don't have access to a computer or mobile device; or - Patients who have a cancer diagnosis. |
Country | Name | City | State |
---|---|---|---|
United States | University of California, San Francisco | San Francisco | California |
Lead Sponsor | Collaborator |
---|---|
University of California, San Francisco |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cancer | While not the primary outcome measure, the development of cancer from a pancreatic cyst is a critically important study endpoint, which the investigators do not expect to be frequent occurrence. | 1-10 years | |
Primary | Indolency | If a patient with a pancreatic cyst experiences no or minimal change in size, and no development of worrisome or high-risk stigmata (Tanaka 2017), this will be considered to be an indolent lesion. Most patients will fall under this category. | 1-10 years |
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