Pancreatic Cancer Clinical Trial
Official title:
Gene Expression Profiles in Primary and Metastatic Pancreatic Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may
help doctors learn more about changes that may occur in DNA and identify biomarkers related
to cancer.
PURPOSE: This laboratory study uses gene expression profiling to compare primary tumor cells
with metastatic tumor cells in patients with metastatic pancreatic cancer.
OBJECTIVES:
- Compare the gene expression profiles of pancreatic cancer cells from the primary and
metastatic sites in patients with metastatic pancreatic cancer.
- Characterize the function of the differentially upregulated and downregulated genes
identified by comparing the gene expression profiles of primary and metastatic cells in
these patients.
OUTLINE: Fresh biopsy samples are collected for gene expression profiling and other
biomarker/laboratory analyses.
PROJECTED ACCRUAL: A total of 10 patients will be accrued for this study.
;
Observational Model: Case-Only, Time Perspective: Prospective
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