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NCT05722548 Clinical Trial

Efficacy of Rectal Indomethacin in Prevention of Post-pancreatectomy Acute Pancreatitis

Pancreatectomy Clinical Trial

Official title:
Efficacy of Rectal Indomethacin in Prevention of Post-pancreatectomy Acute Pancreatitis-A Randomized Controlled Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05722548
Other study ID # LYBWWG2023
Secondary ID
Status Not yet recruiting
Phase Phase 2
First received
Last updated
Start date February 1, 2023
Est. completion date February 1, 2024

Study information
Verified date January 2023
Source Shanghai Jiao Tong University School of Medicine
Contact Yingbin Liu, PHD
Phone +8613918803900
Email laoniulyb@163.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy of rectal indomethacin in prevention of post-pancreatectomy acute pancreatitis.

Description:

The purpose of this study is to evaluate the efficacy of rectal indomethacin in prevention of post-pancreatectomy acute pancreatitis.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 200
Est. completion date February 1, 2024
Est. primary completion date December 31, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria: *All patients planned to undergo pancreatectomy. Exclusion Criteria: - asthma - allergic reactions to NSAIDs - CKD - internal hemorrhoids - anti-platelet medications

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Indomethacin suppository
100mg of Indomethacin Suppository sigle dose at the time of induction of anesthesia
Other:
• Standard Medical Treatment
Standard Medical Treatment

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Shanghai Jiao Tong University School of Medicine

Outcome
Type Measure Description Time frame Safety issue
Primary Post-pancreatectomy Acute Pancreatitis 2 weeks after pancreatectomy
Secondary Pancreatic Fistula 30 days after pancreatectomy
Secondary Peripancreatic abscess 30 days after pancreatectomy
Secondary Length of hospital stay 30 days after pancreatectomy
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