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Pancreatectomy clinical trials

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NCT ID: NCT02509910 Completed - Fluid Therapy Clinical Trials

Implementation of a GDT Algorithm for Major Surgery Patients

Start date: July 2013
Phase: N/A
Study type: Observational

This study examines the effect of an algorithm for GDT for patients undergoing major surgery under routine conditions.

NCT ID: NCT02230436 Recruiting - Pancreatectomy Clinical Trials

Early Versus Late Drain Removal After Pancreatectomy: A Randomized Prospective Trial

Start date: July 2014
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate the hypothesis that early removal of drain can reduce the incidence of intra-abdominal infection and pancreatic fistula after pancreatectomy compared with later removal of drain.

NCT ID: NCT01950845 Completed - Colorectal Surgery Clinical Trials

Automated Versus Manual Fluid Management for High Risk Abdominal Surgical Patient. A Prospective, Randomized Trial

CL vs CP
Start date: February 2014
Phase: N/A
Study type: Interventional

Dynamic parameters like pulse pressure variation have been shown to be accurate predictors of fluid responsiveness. Hemodynamic optimization based on fluid management and stroke volume optimization have been shown to improve patient outcomes, especially for moderate and high risk abdominal surgical patients. A novel closed-loop fluid administration system based on multi-parameter hemodynamic monitoring have been described recently. This prospective, randomized, surgeon and patient blinded study aims at comparing the cardiac output provided by either this closed-loop system or the anesthesiologist team in high-rish surgical patient elected for abdominal surgery at Pierre Bénite University Hospital, Hospices Civils of Lyon, France. Primary endpoint is the mean indexed cardiac output during surgery per group. We will also compare hemodynamic parameter (cardiac output, stroke volume, blood pressure heart rateā€¦) and patient's outcomes (morbidity, mortality, transfusion rate, hospital length of stay) between groups

NCT ID: NCT01929902 Completed - Pancreatectomy Clinical Trials

Evaluation of Efficacy and Accuracy of Aquamantys Device in General Surgery

Start date: July 2013
Phase:
Study type: Observational

The purpose of this study is to test the efficacy and accuracy of the Aquamantys device.

NCT ID: NCT00988793 Withdrawn - Pancreatectomy Clinical Trials

Laparoscopic Versus Open Pancreatectomy

Start date: n/a
Phase: N/A
Study type: Interventional

The study will randomized patients to either open or laparoscopic pancreatic surgery. The primary purpose of the study is to determine whether laparoscopic distal pancreatectomy is associated with improved outcomes compared to open distal pancreatectomy.

NCT ID: NCT00708513 Completed - Hepatectomy Clinical Trials

Intraoperative Cell Saver Autotransfusion Use for Major Surgical Oncology Operations.

Cellsaver
Start date: December 2003
Phase: N/A
Study type: Observational

The purpose of this study is to demonstrate the safety and benefit of auto-transfusion filtered blood in patients undergoing major surgical oncology procedures.

NCT ID: NCT00559364 Completed - Clinical trials for Chronic Pancreatitis

Safety and Efficacy Study of Viokase® 16 for the Correction of Steatorrhea

Start date: November 2007
Phase: Phase 3
Study type: Interventional

This study assesses the efficacy and safety of Viokase® 16 for the correction of steatorrhea (malabsorption of dietary fats) in patients with a history of exocrine pancreatic insufficiency (EPI) due to chronic pancreatitis (CP) or pancreatectomy. This study is sponsored by Aptalis Pharma (formerly Axcan).

NCT ID: NCT00414908 Completed - Clinical trials for Chronic Pancreatitis

A Study to Investigate the Effect of Delayed Release Pancrelipase on Maldigestion in Patients With Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis and Pancreatectomy

Start date: October 2007
Phase: Phase 3
Study type: Interventional

This study assessed the effect of pancrelipase delayed release capsules on fat and nitrogen absorption in subjects with PEI due to Chronic Pancreatitis and Pancreatectomy. There was a run-in with a 5-day of single-blind placebo treatment, followed by a 7-day Double-blind period and a 6-month Open-Label Follow-up.