Pain Clinical Trial - Excitability Protocol: Voltage-gated Ion Channels

Status Active, not recruiting

Clinical Trial Summary

The purpose of subproject 1 is to evaluate the accuracy of a nerve excitability protocol in healthy subjects before testing the protocol in diabetic neuropathy patients. The nerve excitability protocol has been derived by computational modeling to identify abnormalities of three subtypes of ion voltage-gated channels. These three ion channels are all altered in animal models of diabetic neuropathy and, therefore, are likely candidates for generating the altered excitability in diabetic neuropathy patients. The hypothesis for subproject 1 is that due to the unique dynamics of each subtype of voltage-gated ion channels, it is possible to identify abnormal voltage-gated ion channel alterations by altering the shape of the electrical stimulation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Pain

Clinical Trial Details

NCT number	NCT05368532
Study type	Interventional
Source	Aalborg University
Contact
Status	Active, not recruiting
Phase	N/A
Start date	July 31, 2022
Completion date	March 1, 2024

View Details

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