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Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain

Pain Clinical Trial

Official title:
Sciatic Block in Contralateral Limb for Treatment of Refractory Phantom and Residual Limb Pain; a Triple-Blind Randomized Crossover Controlled Trial

Clinical Trial Summary

Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial. Aim: Define the attributable pain relief and functional improvement in participants with PLP/RLP after contralateral limb sciatic nerve block. Also, contribute to the basic science understanding of the crossed-withdraw reflex by demonstrating a known animal model phenomenon in human participants. Hypothesis: Contralateral limb sciatic nerve anesthetic block with 2% lidocaine provides immediate clinically meaningful pain reduction, defined as the proportion of patients with at least 50% improvement in NRS pain score in PLP/RLP when compared to sham.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05046639
Study type Interventional
Source Northwestern University
Contact David Walega, MD, MSCI
Phone (312)926-8369
Email d-walega@northwestern.edu
Status Recruiting
Phase Phase 4
Start date September 1, 2021
Completion date March 2024
View Details
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