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Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain

Pain Clinical Trial

Official title:
A Comparison of Lidocaine, Esmolol, and Placebo Without Use of a Tourniquet for Relieving Pain From Intravenous Administration of Propofol

Clinical Trial Summary

The primary hypothesis is that esmolol and lidocaine, when given without the use of a tourniquet, provide relief of propofol injection pain that is superior to placebo when assessed using the propofol pain scoring tool

Clinical Trial Description

The study will include three arms: lidocaine, esmolol, and placebo. Eligible patients will be 18-60 years old, ASA physical status 1-3, and scheduled for an elective surgical procedure. Patients will be randomized to receive lidocaine, esmolol, or placebo. Both the patients and the administering/observing providers will be blinded to the study drug or placebo being administered ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04356352
Study type Interventional
Source Wake Forest University Health Sciences
Contact
Status Terminated
Phase Phase 2/Phase 3
Start date September 9, 2020
Completion date August 25, 2023
View Details
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