Pain Clinical Trial
Official title:
Effects of Laser Therapy on Pain Intensity for Carpometacarpal Joint Osteoarthritis as a Isolated Treatment. A Randomized (Double-blind) Controlled Trial
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA, only modest treatment effects were reported for most individual interventions. The aim of the proposed study is to assess the effect of laser therapy on pain, function and force in patients with carpometacarpal osteoarthritis (CMC OA).
A randomized, controlled, single-center, double-blind, clinical trial, with 1:1 allocation
ratio, were carried out involving patients diagnosis of CMC joint OA grade 1-2 (aged 18 years
and above). Both assessor and statistician remained blinded. The research diagnostic criteria
for carpometacarpal joint osteoarthritis was used to assess all individuals who agree to
participate. All participants were submitted to a clinical examination and X-ray assessment
of thumb base to determine carpometacarpal osteoarthritis grade. Based on the clinical and
radiological findings, the participants were classified by a rheumatology. Those with CMC OA
grade 2-3 were included in the study. The experimental group received laser therapy and
control group received a placebo treatment.
The primary outcome measures was pain scores during daily living activities (DLA)- at the
base of the thumb measured with VAS (Unidimensional measure of pain: 0-10 (0, no pain and 10,
worst pain), and changes in hand function measured using the Quick-Dash questionnaire.
Secondary outcome measures included changes in pinch strength. All outcome measures were
collected at baseline, immediately following the intervention at 4 weeks and at 12 weeks
following the end of the intervention.
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